Results 91 to 100 of about 1,289,776 (315)

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Persistence and Evolution Within Interactive Design: An Integrated Approach to ICT Innovations in Emergent Game Narratives

Technologies
Video games, as interactive artifacts within the continuum of information and communication technology (ICT), encapsulate an ontological inquiry: which mechanism maintains user engagement while evolving with ICT-driven innovations?
Mengfan Zou, Yuan Meng, Sara Cortés Gómez, Julia Sabina Gutierrez Sánchez   +3 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Bulletin de la documentation collégiale numéro 16 [PDF]

, 2016
Disponible en anglais dans EDUQ.info sous le titre "Summative assessment"Comprend des références bibliographiquesL’évaluation sommative est un sujet presque banal.
Howe, Robert
core  

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Archives and planning for sustainable development models of reality: case study in the archival service of the wilaya of Constantine

Cybrarians Journal, 2019
Interest in archives emerged mainly since the French Revolution. Much more attention was paid to historical documents, especially for their cultural and historical role.
Chahrazed Abada, Intissar Delhoum
doaj   +1 more source

Documentation in Nursing, 1st Canadian edition [PDF]

, 2020
1. Introduction to Documentation2. Reasons for Documentation3. Documentation Components4. Electronic Documentation Systems5. Principles of Documentation6. Privacy, Confidentiality, and Security7. Methods of Documentation8.
St-Amant, Oona, Lapum, Jennifer, Hughes, Michelle, Ronquillo, Charlene, Garmaise-Yee, Joy   +4 more
core  

Documentation for the Sake of Documentation? [PDF]

Circulation, 1999
To the Editor: In their recent study, Frolkis and colleagues1 attempt to determine by chart review how often patients with acute myocardial infarction are counseled to quit smoking and encouraged to exercise. They acknowledge that if no such counseling nor encouragement is documented in the chart, the study assumes none was done. Certainly a patient
openaire   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Status of CCUS research and governance by worldwide geological surveys and organizations

China Geology, 2023
Huan Wang, Jia-jia Xu, Yang Yu
doaj   +1 more source