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Bulletin de la documentation collégiale numéro 8

open access: yes, 2012
Voir aussi : "La réussite scolaire des garçons - partie 1 : problématique et facteurs en cause" (Bulletin de la documentation collégiale n°6, mai 2011), disponible dans EDUQ.infoDisponible en anglais dans EDUQ.info sous le titre "School Success for Boys -
Boisvert, Jacques
core  

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

Archives and planning for sustainable development models of reality: case study in the archival service of the wilaya of Constantine

open access: yesCybrarians Journal, 2019
Interest in archives emerged mainly since the French Revolution. Much more attention was paid to historical documents, especially for their cultural and historical role.
Chahrazed Abada, Intissar Delhoum
doaj   +1 more source

Bulletin de la documentation collégiale numéro 15 [PDF]

open access: yes, 2016
Voir aussi : "La formation de la pensée critique : première partie" (Bulletin de la documentation collégiale n°14, mai 2015), disponible dans EDUQ.infoDisponible en anglais dans EDUQ.info sous le titre "Developing critical thinking : part two"Comprend ...
Boisvert, Jacques
core  

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Bulletin de la documentation collégiale numéro 3

open access: yes, 2010
Disponible en anglais dans EDUQ.info sous le titre "Class Management"Comprend des références bibliographiquesQue l'on pense à l'étudiant qui teste les limites de l'enseignant dès le premier cours ou à l'enseignant qui doit présenter et faire respecter ...
Meloche, François
core   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

A Study of Methods to Identify Industry-University-Research Institution Cooperation Partners based on Innovation Chain Theory

open access: yesJournal of Data and Information Science, 2018
This study aims at identifying potential industry-university-research collaboration (IURC) partners effectively and analyzes the conditions and dynamics in the IURC process based on innovation chain theory.
Xu Haiyun   +5 more
doaj   +1 more source

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