Results 51 to 60 of about 1,675,922 (248)

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Bulletin de la documentation collégiale numéro 6

open access: yes, 2011
Voir aussi : "La réussite scolaire des garçons - partie 2 : actions et pistes d'intervention" (Bulletin de la documentation collégiale n°8, janvier 2012), disponible dans EDUQ.infoDisponible en anglais dans EDUQ.info sous le titre "School Success for ...
Boisvert, Jacques
core   +1 more source

Bulletin de la documentation collégiale numéro 13 [PDF]

open access: yes, 2015
Disponible en anglais dans EDUQ.info sous le titre "Program development at the college"Comprend des références bibliographiquesLe programme d’études est au centre de la formation à tous les ordres d’enseignement.
Picard, Yves
core   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Collaborative weighting in federated graph neural networks for disease classification with the human-in-the-loop

open access: yesScientific Reports
The authors introduce a novel framework that integrates federated learning with Graph Neural Networks (GNNs) to classify diseases, incorporating Human-in-the-Loop methodologies. This advanced framework innovatively employs collaborative voting mechanisms
Christian Hausleitner   +3 more
doaj   +1 more source

The Librarians ‘role in Setting up Digital Libraries projects: A case study of Librarians at the University of Constantine 1

open access: yesCybrarians Journal, 2014
 The need for librarians to shift to the digital environment in terms of work to face the present changes necessitates some thinking about the requirements of this conversion.
Khadidja Boukhalfa, Nadjia Gamouh
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Active Learning and ICT in Upper Secondary School: an Exploratory Case Study on Student Engagement by Debating

open access: yesEAI Endorsed Transactions on e-Learning, 2017
The paper outlines the first phase of a three-year research activity on active learning in the core curriculum subject, intended as a possible solution to student disengagement in secondary schools.
S. Panzavolta, C. Laici
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

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