Results 31 to 40 of about 4,122 (142)

Psoríase e Doença Cardiovascular: Impacto da Terapêutica com Inibidores do TNF-alfa

Revista da Sociedade Portuguesa de Dermatologia e Venereologia, 2018
A psoríase é uma doença inflamatória crónica que atinge 2 a 3% da população. Vários estudos têm demonstrado que a psoríase se associa a um aumento de risco de doença cardiovascular devido ao aumento da prevalência de fatores de risco cardiovasculares ...
Filipa Andrade, Sandra Ferreira, Tiago Torres   +2 more
doaj   +1 more source

Short‐ and Long‐Term Effect of Multidomain Lifestyle Intervention on Frailty: Post Hoc Analysis of an RCT

Journal of the American Geriatrics Society, Volume 73, Issue 8, Page 2457-2465, August 2025.
A Sankey diagram illustrating the flow of participants from baseline frailty status to each follow‐up assessment. Data represents numbers of participants observed in each group. ABSTRACT Background The prevalence of frailty is increasing as the population ages. Lifestyle interventions have shown potential in frailty prevention.
Johanna Pöyhönen, Hanna‐Maria Roitto, Jenni Lehtisalo, Esko Levälahti, Timo Strandberg, Miia Kivipelto, Jenni Kulmala, Riitta Antikainen, Hilkka Soininen, Jaakko Tuomilehto, Tiina Laatikainen, Tiia Ngandu   +11 more
wiley   +1 more source

Psoriasis: The visible killer

Revista Portuguesa de Cardiologia, 2014
Psoriasis is a common chronic inflammatory disease associated with serious comorbidities. In recent years, increased mortality due to cardiovascular disease (myocardial infarction and stroke) has been documented in patients with severe psoriasis ...
Tiago Torres, Nuno Bettencourt
doaj   +1 more source

Avaliação e manejo da doença cardiovascular em pacientes com doença renal crônica Assessment and management of cardiovascular disease in patients with chronic kidney disease

Brazilian Journal of Nephrology, 2010
Doenças cardiovasculares são as principais complicações fatais da doença renal crônica, tanto para pacientes em terapia renal substitutiva quanto para aqueles em tratamento conservador. A análise de seus fatores de risco, abordagem diagnóstica e adequado
Sérgio Gardano Elias Bucharles, Alexandre M Varela, Silvio Henrique Barberato, Roberto Pecoits-Filho   +3 more
doaj   +1 more source

Asymptomatic SARS‐CoV‐2 Infection: Association Involving the HLA‐B*15 Allele Group in Brazilian Individuals

HLA, Volume 105, Issue 6, June 2025.
ABSTRACT The aim of this study was to investigate the influence of HLA‐A, ‐B and ‐C polymorphisms on the clinical course of SARS‐CoV‐2 infection and on the progression of COVID‐19 in a population from southeastern Brazil. This study included 478 unvaccinated individuals. Of these, 369 were hospitalised with critical/severe (n = 309) or moderate/mild (n 
Christiane Maria Ayo, Henrique Magalhães, Marcos Paulo Miola, Cinara Cássia Brandão, Maurício Lacerda Nogueira, Cássia Fernanda Estofolete, Victor Hugo de Souza, Jeane Eliete Laguila Visentainer, Luiz Carlos de Mattos   +8 more
wiley   +1 more source

Alzheimer's Disease Sequencing Project release 4 whole genome sequencing dataset

Alzheimer's &Dementia, Volume 21, Issue 5, May 2025.
Abstract INTRODUCTION The Alzheimer's Disease Sequencing Project (ADSP) is a national initiative to understand the genetic architecture of Alzheimer's disease and related dementias (ADRD) by integrating whole genome sequencing (WGS) with other genetic, phenotypic, and harmonized datasets from diverse populations. METHODS The Genome Center for Alzheimer'
Yuk Yee Leung, Wan‐Ping Lee, Amanda B. Kuzma, Heather Nicaretta, Otto Valladares, Prabhakaran Gangadharan, Liming Qu, Yi Zhao, Youli Ren, Po‐Liang Cheng, Pavel P. Kuksa, Hui Wang, Heather White, Zivadin Katanic, Lauren Bass, Naveen Saravanan, Emily Greenfest‐Allen, Maureen Kirsch, Laura Cantwell, Taha Iqbal, Nicholas R. Wheeler, John J. Farrell, Congcong Zhu, Shannon L. Turner, Tamil I. Gunasekaran, Pedro R. Mena, Yumi Jin, Luke Carter, Alzheimer's Disease Sequencing Project, Xiaoling Zhang, Badri N. Vardarajan, Arthur Toga, Michael Cuccaro, Timothy J. Hohman, William S. Bush, Adam C. Naj, Eden Martin, Clifton L. Dalgard, Brian W. Kunkle, Lindsay A. Farrer, Richard P. Mayeux, Jonathan L. Haines, Margaret A. Pericak‐Vance, Gerard D. Schellenberg, Li‐San Wang   +44 more
wiley   +1 more source

Artrite reumatoide e doença cardiovascular: o que sabemos e o que podemos fazer pelo paciente na atualidade?

Revista Portuguesa de Cardiologia, 2012
Resumo: O interesse em doenças auto-imunes vem crescendo a cada ano, principalmente a inter-relação com as doenças cardiovasculares. Especificamente, a artrite reumatoide vem sendo considerada um fator de risco independente para doença arterial coronária
Alexandre de Matos Soeiro, Michel Haddad, Maria Carolina Feres de Almeida, Aline D. Ruppert, Carlos V. Serrano Jr.   +4 more
doaj   +1 more source

The performance of plasma p‐tau217 in Black middle‐aged and older adults

Alzheimer's &Dementia, Volume 21, Issue 5, May 2025.
Abstract INTRODUCTION Medical conditions prevalent in Black adults within the United States have been associated with plasma tau phosphorylated at threonine 217 (p‐tau217); however, insufficient p‐tau217 research has been conducted with Black adults.
Gilda E. Ennis, Derek Norton, Rebecca E. Langhough, Diane C. Gooding, Fabu P. Carter, Rachael Wilson, Megan Zuelsdorff, Shenikqua Bouges, Sanjay Asthana, Sterling C. Johnson, Henrik Zetterberg, Carey E. Gleason   +11 more
wiley   +1 more source

Fatores de Risco para Doença Cardiovascular em Funcionárias do Hospital de Clínicas de Porto Alegre

Clinical and Biomedical Research, 2011
Introdução: A doença cardiovascular (DCV) é a principal causa de morte em mulheres nos países desenvolvidos. Identificar os fatores de risco para doença cardiovascular modificáveis é imprescindível para atuação dos médicos e demais trabalhadores da ...
Helena von Eye Corleta, Jeruza Lavanholi Neyeloff, Carolina Rocha Barone, Taís Burmann de Mendonça, Julia Barbi Melim, Cristiane Montano Zamboni, Edison Capp, Maria Lúcia da Rocha Oppermann   +7 more
doaj  

Machine learning prediction of tau‐PET in Alzheimer's disease using plasma, MRI, and clinical data

Alzheimer's &Dementia, Volume 21, Issue 2, February 2025.
Abstract INTRODUCTION Tau positron emission tomography (PET) is a reliable neuroimaging technique for assessing regional load of tau pathology in the brain, but its routine clinical use is limited by cost and accessibility barriers. METHODS We thoroughly investigated the ability of various machine learning models to predict clinically useful tau‐PET ...
Linda Karlsson, Jacob Vogel, Ida Arvidsson, Kalle Åström, Olof Strandberg, Jakob Seidlitz, Richard A. I. Bethlehem, Erik Stomrud, Rik Ossenkoppele, Nicholas J. Ashton, Henrik Zetterberg, Kaj Blennow, Sebastian Palmqvist, Ruben Smith, Shorena Janelidze, Renaud La Joie, Gil D. Rabinovici, Alexa Pichet Binette, Niklas Mattsson‐Carlgren, Oskar Hansson   +19 more
wiley   +1 more source