Results 1 to 10 of about 34,771 (206)
Menor Prevalência e Extensão da Aterosclerose Coronária na Doença de Chagas Crônica por Angiotomografia Coronária [PDF]
Resumo Fundamento Em regiões endêmicas da doença de Chagas, por muitos anos, existe uma observação empírica recorrente de que a doença arterial coronariana (DAC) é incomum em pacientes com doença de Chagas.
Savio Cardoso+12 more
doaj +5 more sources
O controle da transmissão da doença de Chagas em Mambaí - Goiás, Brasil (1982-1984) [PDF]
A aplicação de inseticidas em Mambaí-GO, desde 1980, está determinando uma diminuição progressiva inicial de Triatoma infestans no intradomicilio, mas não a sua eliminação. A infestação triatominica foi detectada através de diversos métodos de vigilância
Marco Túlio Antônio García-Zapata+8 more
core +8 more sources
Contribuição ao conhecimento do quadro anatomopatológico do coração na doença de Chagas [PDF]
Os conhecimentos anatomopatológicos da fase aguda humana da doença de Chagas são baseados, quase que em sua totalidade, em trabalhos realizados há várias décadas. Nos últimos anos, mesmo os patologistas de áreas endêmicas da tripanossomíase cruzi não têm
Chapadeiro, Edmundo+4 more
core +9 more sources
Oral transmission of Chagas disease from a One Health approach: A systematic review
Abstract Objective To analyse acute Chagas disease (CD) outbreaks through a qualitative systematic review and discuss the determinants for its prevention and control. Methods Review of studies in which clinical cases of oral transmission were confirmed by parasitological and/or serological tests that included an epidemiological investigation of sources
Alejandra López‐García+1 more
wiley +1 more source
Senescent T cells: Beneficial and detrimental roles
Summary As the thymus involutes during aging, the T‐cell pool has to be maintained by the periodic expansion of preexisting T cells during adulthood. A conundrum is that repeated episodes of activation and proliferation drive the differentiation of T cells toward replicative senescence, due to telomere erosion.
Phatthamon Laphanuwat+2 more
wiley +1 more source
Suppression of TGF‐β/Smad2 signaling by GW788388 enhances DENV‐2 clearance in macrophages
Abstract Dengue fever, caused by the dengue virus (DENV‐1, −2, −3, and −4), affects millions of people in the tropical and subtropical regions worldwide. Severe dengue is correlated with high viraemia and cytokine storm, such as high levels of transforming growth factor‐β1 (TGF‐β1) in the patient's serum.
Gabrielly Sbano Teixeira+7 more
wiley +1 more source
Effects of anti‐Leishmania compounds in the behavior of the sand fly vector Lutzomyia longipalpis
Sugar baits can be used to block the development of Leishmania parasites inside the gut of the vector, adult female sand flies. In this work, we screened a series of synthetic compounds and showed that three of them are suitable for the future development of baits targeting the Leishmania parasites inside the sand fly Lutzomyia longipalpis.
Tainá Neves Ferreira+7 more
wiley +1 more source
Cryptococcus extracellular vesicles properties and their use as vaccine platforms
Abstract Whereas extracellular vesicle (EV) research has become commonplace in different biomedical fields, this field of research is still in its infancy in mycology. Here we provide a robust set of data regarding the structural and compositional aspects of EVs isolated from the fungal pathogenic species Cryptococcus neoformans, C. deneoformans and C.
Juliana Rizzo+16 more
wiley +1 more source
Introduction: Chagas’ disease lacks elements to predict which carriers will evolve into cardiac form and which will remain in undetermined form. Objective: To evaluate the relationship between electrocardiographic evolution and Tpeak–Tend and QT ...
Abilio Augusto Fragata Filho+4 more
doaj +4 more sources
Peptide TT830‐843 from the tetanus toxin is a universal T‐cell epitope. It helps in vaccination and induces T‐cell activation. However, the fine molecular interaction between this antigen and the major histocompatibility complex (MHC) remains unknown.
Artur A. M. L. Brandt+5 more
wiley +1 more source