Results 31 to 40 of about 3,071 (182)

Cortical thickness subtypes in cognitively unimpaired individuals: Differential network and transcriptomic vulnerability to cortical thinning

Alzheimer's &Dementia, Volume 21, Issue 10, October 2025.
Abstract INTRODUCTION The emergence, stability, and contributing factors of Alzheimer's disease (AD) gray matter subtypes remain unclear. METHODS We analyzed data from 1323 individuals without a diagnosis of dementia (CDR < 1) with T1w‐MRI and amyloid‐PET, including 622 with longitudinal data (3.66 ± 1.78 years).
Luigi Lorenzini, Mario Tranfa, Leonard Pieperhoff, Federico Masserini, Mara ten Kate, Lyduine E. Collij, Giuseppe Pontillo, Emma S. Luckett, Alle Meije Wink, Henk JMM Mutsaerts, Tiago Gil Oliveira, Daniele Altomare, Mercè Boada, Anouk den Braber, Cindy Birck, Christopher Buckley, Gill Farrar, Wiesje van der Flier, Giovanni B. Frisoni, Rossella Gismondi, Juan Domingo Gispert, Bernard J. Hanseeuw, Frank Jessen, Marta Marquié, Anja Mett, Craig Ritchie, Gemma Salvadó, Michael Schöll, Mahnaz Shekari, Andrew W. Stephens, Betty M. Tijms, David Vállez García, Rik Vandenberghe, Pieter Jelle Visser, Luca Roccatagliata, Neil P. Oxtoby, Matteo Pardini, Frederik Barkhof   +37 more
wiley   +1 more source

Understanding barriers and optimizing socio‐cognitive assessment in the diagnosis of neurocognitive disorders

Journal of Neuropsychology, Volume 19, Issue 3, Page 603-618, September 2025.
Abstract Harmonized neuropsychological assessment for neurocognitive disorders (NCDs) is an urgent priority in clinics. Neuropsychology assessments in NCDs seldom include tests exploring social cognitive skills. In 2022, we launched the SIGNATURE initiative to optimize socio‐cognitive assessment in NCDs.
Chiara Cerami, Marina Boccardi, Claudia Meli, Andrea Panzavolta, Giulia Funghi, Cristina Festari, Stefano F. Cappa, Thanos Chatzikostopoulos, Christian Chicherio, Florencia Clarens, Fabricio Ferreira de Oliveira, Francesco Di Lorenzo, Marco Filardi, Agustin Ibanez, Nicola Girtler, Thibaud Lebouvier, Giancarlo Logroscino, Antonella Luca, Sarah E. MacPherson, Jordi A. Matias‐Guiu, Tommaso Piccoli, Olivier Piguet, Simone Pomati, Mirella Russo, Leonardo Sacco, Ann‐Katrin Schild, Stefano L. Sensi, Steven D. Shirk, Marc Sollberger, Miguel Tábuas‐Pereira, Magda Tsolaki, Esther van den Berg, Maxime Bertoux, Fiona Kumfor, Jan Van den Stock, Kathleen A. Welsh‐Bohmer, Alessandra Dodich, on behalf of the SIGNATURE initiative   +37 more
wiley   +1 more source

Adaptação dos Familiares Cuidadores de Idosos com Doença de Parkinson: Processo de Transição [PDF]

Psicologia: Teoria e Pesquisa
Resumo Descreveu-se e interpretou-se a repercussão da transição para o exercício do papel de cuidador em familiares de idosos com doença de Parkinson, à luz da teoria das Transições.
Simony Fabíola Lopes Nunes, Angela Maria Alvarez, Rafaela Vivian Valcarenghi, Karina Silveira de Almeida Hammerschmidt, Rafaela Baptista   +4 more
doaj   +2 more sources

Modernizing diagnosis of Alzheimer's disease: A review of global trends and Asia‐specific perspectives

Alzheimer's &Dementia, Volume 21, Issue 8, August 2025.
Abstract The landscape of Alzheimer's disease (AD) and related dementias (ADRD) diagnosis is evolving rapidly, driven by advances in disease understanding, biomarker tools, and disease‐modifying therapies. Modern diagnostic approaches emphasize biological precision, early detection, and dynamic frameworks that adapt to treatment‐induced changes in ...
Takeshi Iwatsubo, Reisa A. Sperling, Alicia Algeciras‐Schimnich, Hidenori Arai, Anna M. Barron, Tammie L. S. Benzinger, Maria C. Carrillo, Christopher Chen, Seong Hye Choi, Igor C. Fontana, Jonathan Graff‐Radford, Joshua D. Grill, Judith Heidebrink, Chaur‐Jong Hu, Ryoko Ihara, Takeshi Ikeuchi, Atsushi Iwata, Fanny C. F. Ip, Fasihah Irfani Fitri, Clifford R. Jack Jr., Jee Hyang Jeong, Jianping Jia, Nagaendran Kandiah, SangYun Kim, Hisatomo Kowa, Renaud La Joie, Yoshiki Niimi, Ryoji Noritake, Ozioma C. Okonkwo, Sebastian Palmqvist, Michael S. Rafii, Rema Raman, Yong Shen, Tanya Simuni, Heather M. Snyder, Orapitchaya Sriwannopas, Luke E. Stoeckel, Wiesje M. van der Flier, Huali Wang, Donna M. Wilcock, Henrik Zetterberg, Jin Zhou, Simin Mahinrad, Claire E. Sexton   +43 more
wiley   +1 more source

Establishing a Research Agenda for Physiotherapy in Portugal: A Delphi Study

Physiotherapy Research International, Volume 30, Issue 3, July 2025.
ABSTRACT Background As physiotherapy research advances, identifying knowledge gaps and setting priorities is crucial for enhancing its efficiency in national and international collaborations. This study aimed to establish a physiotherapy research agenda in Portugal by integrating perspectives from physiotherapists and users of physiotherapy services ...
Isa Silva, Sara Souto‐Miranda, Fernando Ribeiro, Diogo Pires, Maria José Coutinho, Nuno Cordeiro, Eduardo Cruz, Cristina Jácome   +7 more
wiley   +1 more source

Depression in Parkinson's disease: clinical-epidemiological correlates and comparison with a controlled group of non-parkinsonian geriatric patients Depressão na doença de Parkinson: análise clínico-epidemiológica e comparação com um grupo de pacientes geriátricos não parkinsonianos

Brazilian Journal of Psychiatry, 2009
OBJECTIVE: To evaluate and compare the frequency and severity of major depression in patients with Parkinson's disease and in individuals older than 60 years without neurological, rheumatological and/or oncological comorbidities.
Beatriz Azevedo dos Anjos Godke Veiga, Vanderci Borges, Sonia Maria César de Azevedo Silva, Fabrício de Oliveira Goulart, Maysa Seabra Cendoroglo, Henrique Ballalai Ferraz   +5 more
doaj   +1 more source

Exposição a agrotóxicos na agricultura e doença de Parkinson em usuários de um serviço público de saúde do Paraná, Brasil

Cadernos de Saúde Coletiva, 2020
Resumo Introdução A doença de Parkinson e a exposição a agrotóxicos vêm sendo cada vez mais estudadas, haja vista o aumento do consumo dos agrotóxicos, ignorando os efeitos nocivos ao meio ambiente e à saúde humana. Objetivo Analisar a associação entre
Paula Renata Olegini Vasconcellos, Maria Lucia Frizon Rizzotto, Phallcha Luízar Obregón, Herling Gregorio Aguilar Alonzo   +3 more
doaj   +1 more source

Alzheimer's Disease Sequencing Project release 4 whole genome sequencing dataset

Alzheimer's &Dementia, Volume 21, Issue 5, May 2025.
Abstract INTRODUCTION The Alzheimer's Disease Sequencing Project (ADSP) is a national initiative to understand the genetic architecture of Alzheimer's disease and related dementias (ADRD) by integrating whole genome sequencing (WGS) with other genetic, phenotypic, and harmonized datasets from diverse populations. METHODS The Genome Center for Alzheimer'
Yuk Yee Leung, Wan‐Ping Lee, Amanda B. Kuzma, Heather Nicaretta, Otto Valladares, Prabhakaran Gangadharan, Liming Qu, Yi Zhao, Youli Ren, Po‐Liang Cheng, Pavel P. Kuksa, Hui Wang, Heather White, Zivadin Katanic, Lauren Bass, Naveen Saravanan, Emily Greenfest‐Allen, Maureen Kirsch, Laura Cantwell, Taha Iqbal, Nicholas R. Wheeler, John J. Farrell, Congcong Zhu, Shannon L. Turner, Tamil I. Gunasekaran, Pedro R. Mena, Yumi Jin, Luke Carter, Alzheimer's Disease Sequencing Project, Xiaoling Zhang, Badri N. Vardarajan, Arthur Toga, Michael Cuccaro, Timothy J. Hohman, William S. Bush, Adam C. Naj, Eden Martin, Clifton L. Dalgard, Brian W. Kunkle, Lindsay A. Farrer, Richard P. Mayeux, Jonathan L. Haines, Margaret A. Pericak‐Vance, Gerard D. Schellenberg, Li‐San Wang   +44 more
wiley   +1 more source

UEG Week 2022 Poster Presentations

, 2022
United European Gastroenterology Journal, Volume 10, Issue S8, Page 473-1092, October 2022.
wiley   +1 more source

Alzheimer's disease traits in Parkinson's disease without α‐synuclein seeding

Alzheimer's &Dementia, Volume 21, Issue 5, May 2025.
Abstract INTRODUCTION The α‐synuclein (αSyn) seed amplification assay (αSyn‐SAA) is an accurate tool to detect αSyn seeds in patients with Parkinson's disease (PD). However, a minority of clinically diagnosed PD patients are negative for αSyn. METHODS The αSyn‐SAA was performed in cerebrospinal fluid (CSF) of individuals with PD (n = 93), multiple ...
Bárbara Fernandes Gomes, Carly M. Farris, Yihua Ma, Luis Concha‐Marambio, Johanna Nilsson, Karin Forsberg, Russ Lebovitz, Ulf Andreasson, Kaj Blennow, Henrik Zetterberg, David Bäckström   +10 more
wiley   +1 more source