Results 31 to 40 of about 1,127 (131)

ABCA12 Frameshift Deletion in Domestic Cats With Ichthyosis Fetalis

Veterinary Dermatology, Volume 37, Issue 3, Page 365-374, June 2026.
ABSTRACT Background Ichthyosis fetalis (IF), also known as harlequin ichthyosis, is a rare and often fatal autosomal recessive congenital skin disorder. It is characterized by thickened, hard skin plaques and deep skin fissures that limit mobility and cause malformations of the eyes, lips and ears.
Jeanna M. Blake, Melissa P. Swan, Kari J. Ekenstedt   +2 more
wiley   +1 more source

Tolerability and Feasibility of Minimally Invasive Canine Skin Sampling: Excellent Tolerability Meets Transcriptomic Challenges

Veterinary Dermatology, Volume 37, Issue 3, Page 375-385, June 2026.
ABSTRACT Background Advances in transcriptomics have driven the demand for minimally invasive, reproducible and high‐yield skin sampling methods, particularly for studying inflammatory skin diseases in companion animals. Hypothesis/Objectives We tested tolerability, feasibility and RNA quantity and quality of three minimally invasive skin sampling ...
Ina Herrmann, Lisa B. Mamo, Allison N. Dickey   +2 more
wiley   +1 more source

Frailty and Health Outcomes in People 65 Years or Older Living With Dementia: A Systematic Review of the Literature

Journal of the American Geriatrics Society, Volume 74, Issue 3, Page 854-867, March 2026.
ABSTRACT Introduction Although frailty is considered a potentially modifiable risk factor for dementia, its influence on health outcomes in individuals with established dementia remains unclear. This study aims to systematize the current evidence to understand the impact of frailty on the development of adverse outcomes in older adults with dementia ...
Miguel German Borda, Luis Carlos Venegas‐Sanabria, Marco Canevelli, Francesco Landi, Salomón Páez‐García, Kevin O'Hara‐Veintimilla, Lindsay Wallace, Kenneth Rockwood, Tommy Cederholm, Gustavo Duque, Mario Ulises Pérez‐Zepeda, Dag Aarsland   +11 more
wiley   +1 more source

Medical Management of Polycystic Liver Disease: A Position Statement From the European Reference Network on Hepatological Diseases

Liver International, Volume 46, Issue 1, January 2026.
ABSTRACT Polycystic liver disease (PLD) is a rare genetic disorder characterised by progressive liver enlargement due to multiple cysts. The main symptoms are liver volume‐related. Although randomised controlled trials have shown that somatostatin analogues (SSAs) reduce liver volume as well as symptoms, specific guidance on when and how to use SSAs in
Sophia Heinrich, Andreia Margarida Carvalho de Matos, Jordi Colmenero, Ahmed M. Elsharkawy, Soňa Fraňková, Jan Halbritter, Anna Mrzljak, Roman‐Ulrich Müller, Rafaela Pereira, Pavel Strnad, Carmen A. J. Teemer, Jef Verbeek, Karolina M. Wronka, Frederik Nevens, Richard Taubert, Joost P. H. Drenth, on behalf of the European Reference Network on Hepatological Liver Diseases (ERN RARE‐LIVER)   +16 more
wiley   +1 more source

Social representations of oncological patients’ illness process under palliative care at home

Revista de Enfermagem da Universidade Federal de Santa Maria, 2017
Aim: to know social representations of the process of becoming ill as an oncological patient under palliative care in the home context. Method: this is a qualitative, exploratory and descriptive study, which was developed with ten oncological patients ...
Michele Rodrigues Matos, Rosani Manfrin Muniz, Michele Cristiene Nachtigall Barboza, Aline da Costa Viegas, Juliana Amaral Rockembach, Luiz Guilherme Lindemann   +5 more
doaj   +1 more source

Locus coeruleus‐entorhinal cortex tract integrity is linked to plasma tau and glial fibrillary acidic protein

Alzheimer's &Dementia, Volume 21, Issue 12, December 2025.
Abstract INTRODUCTION Pretangle tau inclusions from the locus coeruleus (LC) are hypothesized to propagate to the entorhinal cortex (EC) via neuron‐to‐neuron transmission along its projections. The lower integrity of the LC‐EC pathway accompanying Alzheimer's disease (AD) pathology is supported by post mortem studies, but in vivo evidence remains ...
Yuliya Patsyuk, Maxime Van Egroo, Elise Beckers, Elouise A. Koops, Nicholas J. Ashton, Shorena Janelidze, Kaj Blennow, Oskar Hansson, Henrik Zetterberg, Benedikt A. Poser, Heidi I. L. Jacobs   +10 more
wiley   +1 more source

SINGULARIDADES DO CUIDADO DOMICILIAR DURANTE O PROCESSO DE MORRER: A VIVÊNCIA DE FAMILIARES CUIDADORES

Cogitare Enfermagem, 2009
Trata-se de um estudo etnográfico cujo objetivo foi compreender a experiência de familiares cuidadores que prestavam cuidado diário a um parente doente, sem possibilidades terapêuticas de cura, no ambiente domiciliar. Foi desenvolvido com 16 (dezesseis)
Soraia Matilde Marques
doaj   +1 more source

HLA‐B Serine 116 Confers Protection Against Severe COVID‐19 in a Cohort From Rio de Janeiro, Brazil

HLA, Volume 106, Issue 6, December 2025.
ABSTRACT COVID‐19 is a respiratory disease caused by SARS‐CoV‐2, in which severe outcomes are primarily driven by an exacerbated immune response. The HLA region has been extensively investigated in COVID‐19 due to its central role in the immune response, although genetic associations vary across populations.
Maria Aparecida da Silva Pereira, Sâmila Natiane Ferreira, Cássia Cristina Alves Gonçalves, Mirella Carneiro dos Reis, Carolina da Paz Zampier, Isabela de Carvalho Leitão, Monique de Souza Almeida Lopes, Artur Duque Rossi, Sheila Coelho Soares‐Lima, Rafael Mello Galliez, Shana Priscila Coutinho Barroso, Orlando da Costa Ferreira Junior, Amilcar Tanuri, Terezinha Marta Pereira Pinto Castiñeiras, Átila Duque Rossi, Cynthia Chester Cardoso   +15 more
wiley   +1 more source

Morte e castração: um estudo psicanalítico sobre a doença terminal infantil

Psicologia: Ciência e Profissão
Com o objetivo abordar a questão da doença terminal em pacientes pediátricos, este artigo visa promover uma reflexão sobre a maneira como a criança enferma lida com a morte, bem como seus pais, irmãos e profissionais da área da saúde.
Mônica de Oliveira Gonçalves
doaj   +3 more sources

Qualidade de vida de pacientes renais crônicos terminais em uso de terapia renal substitutiva

Revista Enfermagem Contemporânea, 2020
OBJETIVO: identificar os fatores relacionados às terapias renais substitutivas que interferem na qualidade de vida de pacientes renais crônicos terminais.
Marilaine Matos de Menezes Ferreira, Lara Terezinha Cunha Pereira   +1 more
doaj   +1 more source