Results 21 to 30 of about 862,462 (172)

Acute Neurological Manifestations in COVID‐19 Are Associated With Complement Activation and Glia‐Promoted Neuroinflammation

open access: yesJournal of Medical Virology, Volume 98, Issue 10, October 2026.
ABSTRACT Pathophysiological mechanisms of neurological manifestations in COVID‐19 are not fully known yet. In this case‐control study, proteomic analysis was used to characterize cerebrospinal fluid (CSF) samples from COVID‐19 patients with acute neurological manifestations primarily categorized as: isolated refractory headache (n = 12), encephalopathy
Nicole Lardini Freitas   +8 more
wiley   +1 more source

Terminal City To Do List [PDF]

open access: yes, 2001
Listings from Terminal City Weekly including LIVE Biennial events.

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Encadeamentos da Doença Renal Crônica e o impacto na qualidade de vida de pacientes em hemodiálise

open access: yesRevista Pró-UniverSUS, 2020
A doença renal crônica (DRC) trata-se de enfermidade caracterizada pela perda permanente e irreversível das funções dos rins, comumente associada a diabetes mellitus e hipertensão arterial e que pode progredir para uma fase mais severa, chamada de ...
Wanderson Alves Ribeiro   +3 more
doaj   +3 more sources

Epidemiologia da doença renal policística em pacientes renais crônicos no município de Campinas

open access: yesServiço Social & Saúde, 2015
A carência de dados epidemiológicos da Insuficiência Renal Crônica Terminal (IRCT) no município de Campinas levou a realização deste estudo descritivo, que tomou como recorte a Doença Renal Policística, doença hereditária, passível de interferências ...
Zelia Zilda Lourenço de Camargo Bittencourt
doaj   +1 more source

SORL1 variant links endosomal amyloid precursor protein mis‐sorting to axonal transport defects and neuronal dysfunction

open access: yesAlzheimer's &Dementia, Volume 22, Issue 8, August 2026.
Abstract INTRODUCTION SORL1 encodes the sorting receptor SORLA, a major genetic contributor to Alzheimer's disease (AD). Although SORL1 loss disrupts endosomal trafficking and promotes amyloidogenic amyloid precursor protein (APP) processing, the functional consequences of specific missense variants in human neurons remain unclear.
Miriam Lep   +16 more
wiley   +1 more source

Unveiling the procoagulant state in Alzheimer's disease: A novel PET imaging strategy

open access: yesAlzheimer's &Dementia, Volume 22, Issue 7, July 2026.
Abstract INTRODUCTION A subset of Alzheimer's disease (AD) patients exhibits a procoagulant state that remains undiagnosed despite available treatments. We developed positron emission tomography (PET) strategies to in vivo detect cerebral microthrombi in TgCRND8 mice. METHODS PET was performed with a fibrin‐binding probe (FBP) in TgCRND8 and wild‐type
Carlos Ceron   +22 more
wiley   +1 more source

First Revision of the Guidelines for the Diagnosis and Management of Remethylation Disorders

open access: yesJournal of Inherited Metabolic Disease, Volume 49, Issue 4, July 2026.
ABSTRACT This guideline summarizes diagnostic and therapeutic approaches based on a systematic literature review and evidence evaluation using the GRADE methodology. Given the limited high‐quality data, expert consensus was additionally obtained through a modified Delphi process.
Giorgia Olivieri   +26 more
wiley   +1 more source

Assessing D‐Squame as a Minimally Invasive Technique to Evaluate the Cutaneous Immune Response mRNA in a Dog Model of Canine Atopic Dermatitis

open access: yesVeterinary Dermatology, Volume 37, Issue 3, Page 353-364, June 2026.
ABSTRACT Background Canine atopic dermatitis (cAD) is a multifactorial, inherited skin disease, estimated to affect ≤ 15% of dogs. Studies of skin messenger mRNA in cAD currently use invasive methods, including blood sampling and biopsy collection, whilst advances in human atopic dermatitis study methodology have demonstrated reliable use of minimally ...
Xavier Langon   +5 more
wiley   +1 more source

Vivendo com a doença de Parkinson [PDF]

open access: yes, 2015
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Programa de Pós-Graduação em Enfermagem, Florianópolis, 2015.Este estudo teve como objetivo compreender os significados que as pessoas com doença de Parkinson ...
Valcarenghi, Rafaela Vivian
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Social representations of oncological patients’ illness process under palliative care at home

open access: yesRevista de Enfermagem da Universidade Federal de Santa Maria, 2017
Aim: to know social representations of the process of becoming ill as an oncological patient under palliative care in the home context. Method: this is a qualitative, exploratory and descriptive study, which was developed with ten oncological patients ...
Michele Rodrigues Matos   +5 more
doaj   +1 more source

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