Results 41 to 50 of about 1,129 (131)

A Comprehensive Molecular and Serological Investigation of Hepatitis A Virus Among Patients With Suspected Acute Hepatitis: A Brazilian Study

Journal of Medical Virology, Volume 97, Issue 6, June 2025.
ABSTRACT Hepatitis A Virus (HAV) infects millions of individuals annually and is a major cause of acute viral hepatitis worldwide. This study aims to (1) assess HAV infection in suspected acute hepatitis patients at public healthcare institutions in Brazil; (2) evaluate the proportion of immunized individuals against HAV; (3) identify HAV genotypes; (4)
Ketty Gleyzer de Oliveira, Mariana Pinheiro Alves Vasconcelos, Julia Teixeira Ton, Silvia Naomi de Oliveira Uehara, Roberta Sitnik, Denize Ornelas Pereira Salvador de Oliveira, Layze Castberg, Ricardo Andreotti Siqueira, Peter James Robinson, Thaís Senna de Paula Domingues, Caroline Thomas Panico, César Augusto Inoue, Maira Marranghello Maluf, Fernanda de Mello Malta, Deyvid Amgarten, Erick Dorlass, Pedro Sebe, Arlene S. Pinto, Cirley M. D. O. Lobato, Adalgisa Ferreira, Elodie Hyppolito, Raymundo Paraná, Maria Isabel Schinoni, Edmundo Pessoa de Almeida Lopes, Magali C. Luiz, Raquel F. L. Garcia, Dennis Armando Bertolini, Mário Reis Álvares‐da‐Silva, Raul Salinas Arrojo, Eduardo Emerim, Gabriela P. Coral, Paulo R. Acosta, Marcello Lucena, Rosângela Teixeira, Mônica da Costa Guedes, Livia Melo Villar, Lia Lewis Ximenez, Clarice Gdalevici, Maria Cássia Jacintho Mendes‐Correa, Flair José Carrilho, Gerson Sobrinho Salvador de Oliveira, Paulo Roberto A. Ferreira, Maria Lucia Gomes Ferraz, Ana Catharina de Seixas Santos Nastri, Pablo Andres Munoz Torres, Glória Selegatto, Luciana Vilas Boas Casadio, Simone Tenore, Olavo Henrique Munhoz Leite, Fernanda Fernandes Souza, Tania Reuter, Francisco Souto, Michele Nascimento‐Sales, Ana Paula Maciel Gurski, Andréa Salomão, Bruna Emanuelle Alvarenga Fanis, Maria Cristina Pimenta, Elton Carlos de Almeida, Flávia Moreno Alves de Souza, Gerson Fernando Mendes Pereira, Mario Peribañez Gonzalez, Michele Soares Gomes‐Gouvea, Raymundo Soares de Azevedo, João Renato Rebello Pinho   +63 more
wiley   +1 more source

Inter‐Rater Disagreements in Applying the Montreal Classification for Crohn's Disease: The Five‐Nations Survey Study

United European Gastroenterology Journal, Volume 13, Issue 5, Page 685-696, June 2025.
ABSTRACT Background The Montreal classification has been widely used in Crohn's disease since 2005 to categorize patients by the age of onset (A), disease location (L), behavior (B), and upper gastrointestinal tract and perianal involvement. With evolving management paradigms in Crohn's disease, we aimed to assess the performance of gastroenterologists
Offir Ukashi, Aurelien Amiot, David Laharie, Luis Menchén, Ana Gutiérrez, Samuel Fernandes, Tommaso Pessarelli, Fábio Correia, Carlos Gonzalez‐Muñoza, Julia López‐Cardona, Giulio Calabrese, Rocio Ferreiro‐Iglesias, Natalie Tamir‐Degabli, Nikolas Konstantine Dussias, Amjad Mousa, Raquel Oliveira, Nicolas Richard, Ido Veisman, Kassem Sharif, Shomron Ben‐Horin, Carlos Soutullo‐Castiñeiras, Gabriele Dragoni, Silvia Rotulo, Agnese Favale, Louis Calméjane, Thomas Bazin, Alfonso Elosua, Sara Lopes, Carla Felice, Violeta Mauriz, Inês Coelho Rodrigues, Julia Jougon, Inês Botto, Helena Tavares de Sousa, Lorenzo Bertani, Paula Ripoll Abadía, Alice De Bernardi, Yamile Zabana, Xavier Serra‐Ruiz, Anna Viola, Manuel Barreiro‐de Acosta, Henit Yanai, Alessandro Armuzzi, Fernando Magro, Uri Kopylov   +44 more
wiley   +1 more source

Alzheimer's disease traits in Parkinson's disease without α‐synuclein seeding

Alzheimer's &Dementia, Volume 21, Issue 5, May 2025.
Abstract INTRODUCTION The α‐synuclein (αSyn) seed amplification assay (αSyn‐SAA) is an accurate tool to detect αSyn seeds in patients with Parkinson's disease (PD). However, a minority of clinically diagnosed PD patients are negative for αSyn. METHODS The αSyn‐SAA was performed in cerebrospinal fluid (CSF) of individuals with PD (n = 93), multiple ...
Bárbara Fernandes Gomes, Carly M. Farris, Yihua Ma, Luis Concha‐Marambio, Johanna Nilsson, Karin Forsberg, Russ Lebovitz, Ulf Andreasson, Kaj Blennow, Henrik Zetterberg, David Bäckström   +10 more
wiley   +1 more source

Nefropatia isquêmica Ischemic nephropathy

Jornal Vascular Brasileiro, 2012
A doença renal isquêmica ou nefropatia isquêmica relacionada à doença renovascular pode evoluir de forma rápida e progressiva para a insuficiência renal crônica.
Marcelo Salame, Geórgia Andrade Padulla, Raquel Rodrigues Muradás, Gabriela Machado, Stela Karine Braun, Karine Rabuske dos Santos, Alexandre Valério Mussio, Clóvis Luis Konopka   +7 more
doaj   +1 more source

Plasma p‐tau212 as a biomarker of sporadic and Down syndrome Alzheimer's disease

Alzheimer's &Dementia, Volume 21, Issue 4, April 2025.
Abstract BACKGROUND All individuals with Down syndrome (DS) will develop full‐blown Alzheimer´s disease (AD) pathology by age 40. Several genes encoded in chromosome 21, including dual‐specificity tyrosine phosphorylation‐regulated kinase 1A (DYRK1A), have been proven to contribute to the pathology. Phosphorylation of tau at threonine‐212 (p‐tau212) is
Przemysław R. Kac, Daniel Alcolea, Laia Montoliu‐Gaya, Susana Fernández, Juan Lantero Rodriguez, Lucía Maure, Fernando González‐Ortiz, Bessy Benejam, Michael Turton, Isabel Barroeta, Peter Harrison, Laura Videla, Nicholas J. Ashton, Alberto Lleó, Henrik Zetterberg, María Carmona‐Iragui, Thomas K. Karikari, Juan Fortea, Kaj Blennow   +18 more
wiley   +1 more source

Data‐driven evaluation of suitable immunogens for improved antibody selection

Protein Science, Volume 34, Issue 4, April 2025.
Abstract Antibodies are indispensable in laboratory and clinical applications due to their high specificity and affinity for protein antigens. However, selecting the right protein fragments as immunogens for antibody production remains challenging. Leveraging the Human Protein Atlas, this study systematically evaluates immunogen properties aiming to ...
Katharina Waury, Hlin Kvartsberg, Henrik Zetterberg, Kaj Blennow, Charlotte E. Teunissen, Sanne Abeln   +5 more
wiley   +1 more source

Serum Neutrophil Biomarkers to Predict Crohn's Disease Progression and Infliximab Treatment Outcomes

United European Gastroenterology Journal, Volume 13, Issue 2, Page 229-239, March 2025.
ABSTRACT Background and aims Predicting the treatment outcomes of biological therapies is an unmet need in Crohn's Disease. In this study, we explored the potential of serum neutrophil‐related biomarkers to predict infliximab therapeutic results and disease progression in Crohn's Disease patients, over a 2‐year period, in a real‐world setting.
D. Magalhaes, M. Santiago, M. Patita, B. Arroja, P. Lago, I. Rosa, H. T. Sousa, P. Ministro, I. Mocanu, A. Vieira, J. Castela, J. Moleiro, J. Roseira, C. Eugenia, P. Sousa, F. Portela, L. Correia, S. Dias, J. Afonso, S. Danese, L. Peyrin‐Biroulet, C. C. Dias, F. Magro, on behalf of GEDII, M. Santiago, M. Patita, B. Arroja, P. Lago, I. Rosa, H. T. Sousa, P. Ministro, I. Mocanu, A. Vieira, J. Castela, J. Moleiro, J. Roseira, C. Eugenia, P. Sousa, F. Portela, L. Correia, S. Dias, F. Magro   +41 more
wiley   +1 more source

Um caso de recuperação da função renal na síndrome hemolítico-urêmica tratada com eculizumab

Brazilian Journal of Nephrology, 2016
Resumo A síndrome hemolítico-urêmica atípica (SHUa) é uma doença grave, pouco prevalente, com acometimento em qualquer idade e apresentação esporádica ou familiar. A SHUa é causada por uma ativação descontrolada do sistema complemento. A plasmaférese foi
João Samuel de Holanda Farias, João Pedro Pereira da Cunha, Caio Cesar Cervi Lagana, Maíra Carvalho Gallucci, Domingos Candiota Chula, Maria Fernanda Soares, Marcelo Mazza Nascimento   +6 more
doaj   +1 more source

Síndrome Hemolítico-Urêmica na infância

Brazilian Journal of Nephrology, 2014
O grupo de doenças que podem manifestar-se com MAT podem apresentar superposição clínica, dificultando o diagnóstico diferencial. Entre estas ressaltamos a PTT e SHU, sendo que esta última pode ocorrer pela ação de toxinas, doenças sistêmicas ...
Maria Helena Vaisbich
doaj   +1 more source

Estudo das alterações ecocardiográficas nos primeiros seis meses após o transplante renal

Arquivos Brasileiros de Cardiologia, 2012
FUNDAMENTO: Alterações cardíacas são muito frequentes nos indivíduos portadores de doença renal crônica terminal e estão associadas com a morbimortalidade. OBJETIVOS: Avaliar as alterações evolutivas cardíacas após o transplante renal.
Francival Leite de Souza, Karenn Barros Bezerra, Andréa Rodrigues Sousa, Teresa Cristina Alves Ferreira, Maria Inês Gomes Oliveira, Giovanna Parada Martins, Fernando Alberto Costa Cardoso Silva, Alcione Miranda Santos, Natalino Salgado Filho   +8 more
doaj