Results 11 to 20 of about 9,957 (135)

Primary Anti-Phospholipid Antibody Syndrome: Real-World Defining Features of Rethrombosis in the Course of Disease. [PDF]

Int J Rheumatol, 2022
Objective. We aimed to identify features that allow differentiation of primary antiphospholipid syndrome (PAPS) patients that suffer recurrent thrombotic events (RTE) despite anticoagulation, from the other diagnosed PAPS patients. Methods. This was an exploratory study of anticoagulated PAPS patients attending an Autoimmune Diseases Unit (1998‐2018 ...
Moraes-Fontes MF, Pedro F, Campos MM, Fernandes M, Yavuz S, Oliveira F, Panarra A.   +6 more
europepmc   +2 more sources

Células T regulatórias naturais (T REGS) em doenças reumáticas Natural regulatory T cells in rheumatic diseases [PDF]

Revista Brasileira de Reumatologia, 2008
O sistema imune sadio deve manter o balanço entre a capacidade de responder a agentes infecciosos e de sustentar a autotolerância. A ausência de resposta adequada submete o indivíduo aos efeitos deletérios da invasão por patógenos, ao passo que o sistema
Wilson de Melo Cruvinel, Danilo Mesquita Jr., Júlio Antônio Pereira Araújo, Karina Carvalho Salmazi, Esper Georges Kállas, Luis Eduardo Coelho Andrade   +5 more
doaj   +4 more sources

Vaccination of Adult Patients with Systemic Lupus Erythematosus in Portugal. [PDF]

Int J Rheumatol, 2016
In the wake of the Portuguese vaccination program 50th anniversary it seems appropriate to review vaccination in patients with systemic lupus erythematosus. Controversial issues as regards the association between autoimmune diseases, infections, and vaccines are discussed as well as vaccine safety and efficacy issues as regards chronic ...
Moraes-Fontes MF, Antunes AM, Gruner H, Riso N.   +3 more
europepmc   +2 more sources

Neuropsychiatric features of a cohort of patients with systemic lupus erythematosus. [PDF]

ISRN Rheumatol, 2012
In order to establish if neuropsychiatric systemic lupus erythematosus (NPSLE) can be identified by any characteristic other than those used to diagnose the neuropsychiatric (NP) disease itself, we retrospectively reviewed 98 systemic lupus erythematosus (SLE) patients followed over a mean period of 10 years. NPSLE was identified in 22 patients. Stroke
Moraes-Fontes MF, Lúcio I, Santos C, Campos MM, Riso N, Vaz Riscado M.   +5 more
europepmc   +2 more sources

Genetic and humoral autoimmunity markers of type 1 diabetes: from theory to practice [PDF]

, 2008
Type 1 A diabetes mellitus (T1AD) results from the autoimmune destruction of the insulin producing pancreatic beta-cells. The largest contribution to genetic susceptibility comes from several genes located in the major histocompatibility complex on ...
Davini, Elaine, Mory, Denise, Silva, Maria Elizabeth Rossi da   +2 more
core   +5 more sources

Heterogeneous lupus-specific lesions and treatment outcome, in a single patient, over a period of time. [PDF]

Clin Case Rep, 2019
The report highlights the importance of strict clinico-histological correlations when skin biopsies are performed in diagnostic doubt in systemic lupus erythematosus.
Fernandes M, Taulaigo AV, Vidal C, Agostini P, Riso N, Moraes-Fontes MF.   +5 more
europepmc   +4 more sources

How to interpret and appropriately appreciate the antinuclear antibody test [PDF]

, 2007
The tradicional fluorescent antinuclear antibody test (ANA) has required constant update efforts from personel involved in performing and interpreting its results.
Andrade, Luiz Eduardo Coelho, Dellavance, Alessandra   +1 more
core   +3 more sources

Primary adrenal insufficiency in adults: 150 years after Addison [PDF]

, 2004
Thomas Addison first described, 150 years ago, a clinical syndrome characterized by salt-wasting and skin hyperpigmentation, associated with a destruction of the adrenal gland.
Alvarenga, Daniela B. de, Castro, Margaret de, Cunha, Andréa Aparecida, Elias, Lucila L.k., Kater, Claudio Elias, Moraes, Andréia M. de, Moreira, Ayrton C., Silva, Regina do Carmo   +7 more
core   +4 more sources

Significance of epitope spreading in the pathogenesis of pemphigus vulgaris and foliaceus [PDF]

, 2008
Os pênfigos são dermatoses bolhosas auto-imunes, em que há a produção de auto-anticorpos direcionados contra moléculas de adesão dos epitélios, levando à perda da coesão celular.
AOKI, Valéria, LAGO, Fernanda, MARUTA, Celina Wakisaka, SANTI, Cláudia Giuli, The Cooperative Group on Fogo Selvagem Research, YAMAZAKI, Márcia Harumi   +5 more
core   +2 more sources

Definições para a padronização da pesquisa de auto-anticorpos contra constituintes do núcleo (FAN HEp-2), nucléolo, citoplasma e aparelho mitótico e suas associações clínicas [PDF]

, 2003
OBJECTIVE: The Second Brazilian Consensus on Antinuclear Antibodies (ANA) in HEp-2 Cells approved and extended the decision trees developed during the First Brazilian Consensus in order to also offer information about mixed patterns of fluorescence ...
Andrade, Luiz Eduardo Coelho, Araújo, Flávia Ikeda e, Bichara, Carlos David Araújo, Bonfá, Eloisa Silva Dutra de Oliveira, Callado, Maria Roseli, Carballo, Orlando Gabriel, Carvalho, Darlene Gonçalves, Cintra, Alice Friedenberg de Ulhôa, Cruvinel, Wilson de Melo, Dellavance, Alessandra, Doi, Elvira M., Francescantonio, Paulo Luiz Carvalho, Gabriel Júnior, Alexandre, Guimarães, Fabiana Nunes de Carvalho, Jarach, Renata, Leser, Paulo Guilherme, Levy, Roger Abramino, Mangueira, Cristóvão Luis Pitangueiras, Mesquita, Mauro Meira, Moreira, Caio, Mundim, Hugo Mendonça, Neves, Suzane Pretti Figueiredo, Nuccitelli, Barbara, Poli, Luciana, Rego, Jozelia, Santos, Cláudio Henrique Ramos dos, Santos, Wilton Silva dos, Silva, Nilzio Antônio da, Slhessarenko, Natasha, Sugiyama, Mitiko, Taliberti, Ben Hur, Vieira, Lisiane Ericonio dos Anjos, Von Mühlen, Carlos Alberto, Xavier, Ricardo Machado, Ximenes, Antônio Carlos, Yano, Cristiane Martinez   +35 more
core   +3 more sources