Results 101 to 110 of about 1,709,554 (389)

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Pilot Testing a Qualitative Methodology to Evaluate the Perceived Benefits and Stressors of Sole-Dog Ownership in Full-time College Students [PDF]

open access: yes, 2020
The number of individuals acquiring pets is continually increasing, with 71.5% of Americans owning a pet in 2012. Companion animals are a huge source of benefits but owning them can also come with several stressors.
Williams, Emma
core   +2 more sources

Patient benefit of dog-assisted interventions in health care: a systematic review

open access: yesBMC Complementary and Alternative Medicine, 2017
BackgroundDogs are the most common companion animal, and therefore not surprisingly a popular choice for animal-assisted interventions. Dog-assisted interventions are increasingly used in healthcare.
M. Lundqvist   +4 more
semanticscholar   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

Frequency estimation of disease-causing mutations in the Belgian population of some dog breeds, part 1 : shepherds [PDF]

open access: yes, 2016
In light of improving breeding advice, the frequency was estimated for all the disease-causing mutations that were known at the start of the study and that are potentially relevant for a group of dog breeds, which are relatively popular or in which the ...
Beckers, Evy   +3 more
core   +1 more source

Physiological reactivity to spontaneously occurring seizure activity in dogs with epilepsy and their carers [PDF]

open access: yes, 2017
There is a complex bidirectional relationship between stress and epilepsy. Stressful stimuli and subsequent cortisol release act as a trigger for seizure activity in some individuals with epilepsy, and seizure activity itself may act as a stressor to the
Fowkes, R C, Packer, R M A, Volk, H A
core   +1 more source

Dog Population & Dog Sheltering Trends in the United States of America

open access: yesAnimals, 2018
Simple Summary The pet overpopulation problem in the United States has changed significantly since the 1970s. The purpose of this review is to document these changes and propose factors that have been and are currently driving the dog population dynamics
A. Rowan, Tamara Kartal
semanticscholar   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

open access: yesMolecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy   +9 more
wiley   +1 more source

Deadly Predators and Virtuous Buddhists: Dog Population Control and the Politics of Ethics in Ladakh [PDF]

open access: yes, 2019
The region of Ladakh in the Indian Himalayas has recently seen a rise in attacks by stray dogs, some of which have been fatal. The dogs’ claims on territory have not gone uncontested in an emotional landscape fraught with anxieties over religious ...
Gagné, Karine
core   +1 more source

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