Results 61 to 70 of about 1,447,809 (294)

Rabies elimination research: juxtaposing optimism, pragmatism and realism [PDF]

open access: yes, 2017
More than 100 years of research has now been conducted into the prevention, control and elimination of rabies with safe and highly efficacious vaccines developed for use in human and animal populations. Domestic dogs are a major reservoir for rabies, and
Bögel K   +13 more
core   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

open access: yesFEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

The impact of COVID-19 and bushfires on the mental health of Australian adolescents: a cross-sectional study

open access: yesChild and Adolescent Psychiatry and Mental Health, 2023
Background When COVID-19 spread to Australia in January 2020, many communities were already in a state of emergency from the Black Summer bushfires. Studies of adolescent mental health have typically focused on the effects of COVID-19 in isolation.
Joanne R. Beames   +8 more
doaj   +1 more source

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

open access: yesMolecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser   +11 more
wiley   +1 more source

Men’s mental health and suicide prevention service landscape in Australia: a scoping review

open access: yesBMC Public Health
Background Men represent the majority of suicide deaths globally and men are more likely to die by suicide without contact with formal mental health services. In Australia, three-quarters of suicide deaths are men.
Aimy Slade   +6 more
doaj   +1 more source

Therapeutic ultrasound as an aid in tibial fracture management in a dog [PDF]

open access: yes, 2017
A six-year-old, male, neutered Bernese mountain dog was presented with acute left hind limb lameness. Based on the symptoms, orthopedic examination and radiographic evaluation, a cranial cruciate ligament rupture was diagnosed.
de Bakker, Evelien   +3 more
core   +1 more source

Successful medical management of an epidural abscess in a dog [PDF]

open access: yes, 2017
A seven-month-old entire male dobermann presented with acute onset neck pain and left thoracic limb lameness. The dog had a similar episode eight weeks before presentation that responded to meloxicam.
Durand, Alexane   +3 more
core   +1 more source

Expression and DNA methylation of 20S proteasome subunits as prognostic and resistance markers in cancer

open access: yesMolecular Oncology, EarlyView.
Comprehensive analysis of genomic mutations, gene expression, DNA methylation, and pathway analysis of TCGA data was carried out to define cancer types in which proteasome subunits expression is associated with worse survival. Albeit the effect of specific proteasome subunits on cellular function, the main role of the proteasome is better evaluated ...
Ruba Al‐Abdulla   +5 more
wiley   +1 more source

Do owners have a Clever Hans effect on dogs? Results of a pointing study

open access: yesFrontiers in Psychology, 2012
Dogs are exceptionally successful at interpreting human pointing gestures to locate food hidden in one of two containers. However, whether dogs are totally reliant on the pointing gesture itself, or if their success is increased by subtle cues from their
Teresa eSchmidjell   +11 more
doaj   +1 more source

Pilot Testing a Qualitative Methodology to Evaluate the Perceived Benefits and Stressors of Sole-Dog Ownership in Full-time College Students [PDF]

open access: yes, 2020
The number of individuals acquiring pets is continually increasing, with 71.5% of Americans owning a pet in 2012. Companion animals are a huge source of benefits but owning them can also come with several stressors.
Williams, Emma
core   +2 more sources

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