Results 71 to 80 of about 1,709,554 (389)
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Necrotizing meningoencephalitis in atypical dog breeds: a case series and literature review. [PDF]
, 2014 BackgroundCanine necrotizing meningoencephalitis (NME) is a fatal, noninfectious inflammatory disease of unknown etiology. NME has been reported only in a small number of dog breeds, which has led to the presumption that it is a breed-restricted disorder.
Cooper, JJ +7 more
core +1 more source
Frontiers in Veterinary Science, 2017 Free-roaming dogs and rabies transmission are integrally linked across many low-income countries, and large unmanaged dog populations can be daunting to rabies control program planners.
L. Taylor +7 more
semanticscholar +1 more source
The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
Exploring the lived experience of mental health and coping during unemployment
BMC Public Health, 2022 Background Unemployment is known to involve various psychosocial challenges that can negatively impact mental health. However, the intricacies of how individuals experience these challenges and strive to cope within the context of varied sociocultural ...
Andrew F. Arena +5 more
doaj +1 more source
A report on child safety and dog attacks [PDF]
, 2000 The research investigated the issues involving dog attacks on children, specifically by dogs known to the child. The report identifies the circumstances and conditions which may result in an attack by a family dog.
Bennett, Ursula +2 more
core +1 more source
Successful medical management of an epidural abscess in a dog [PDF]
, 2017 A seven-month-old entire male dobermann presented with acute onset neck pain and left thoracic limb lameness. The dog had a similar episode eight weeks before presentation that responded to meloxicam.
Durand, Alexane +3 more
core +1 more source
Scientific Reports, 2019 A temporal decline in human and dog sperm quality is thought to reflect a common environmental aetiology. This may reflect direct effects of seminal chemicals on sperm function and quality.
R. Sumner +4 more
semanticscholar +1 more source
Integration of circadian and hypoxia signaling via non‐canonical heterodimerization
FEBS Letters, EarlyView.CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley +1 more source
AnimalsDesigner dogs—the result of intentionally crossbreeding purebred dogs, and specifically poodle mixes (a cross between a poodle and a second breed)—have rapidly grown in popularity in recent years [...]
Amanda J. Venturino +3 more
doaj +1 more source