Results 51 to 60 of about 629,087 (258)

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Responsible Dog Ownership workshop data

open access: yes, 2019
Randomised controlled trial data collected as part of an impact assessment for Responsible Dog Ownership workshops aiming to increase children's attitudes towards responsible ...
Katharine Anderson (7363094)
core   +1 more source

Variable summary statistics for Be Dog Smart workshop and Responsible Dog Ownership workshops.

open access: yes, 2020
Variable summary statistics for Be Dog Smart workshop and Responsible Dog Ownership workshops.
Anna Baatz (8561224)   +6 more
core   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

open access: yesFEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard   +12 more
wiley   +1 more source

Association between dog ownership and type 2 diabetes in later life: the Helsinki birth cohort study

open access: yesInternational Journal of Circumpolar Health, 2019
Dog ownership has been reported to have beneficial effects on physical activity and emotional well-being, both known to reduce the risk for type 2 diabetes (T2D).
Merja K. Laine   +6 more
doaj   +1 more source

Associations of dog and cat ownership with wheezing and asthma in children: Pilot study of the Japan Environment and children's study.

open access: yesPLoS ONE, 2020
OBJECTIVES:No previous study has used repeated measures data to examine the associations of dog/cat ownership with wheezing and asthma prevalence among children.
Yu Taniguchi   +15 more
doaj   +1 more source

“In times of stress, it is good to be with them”: experience of dog owners from a rural district of Sri Lanka

open access: yesBMC Public Health, 2022
Background The dog has been man’s best companion since ancient times. And, dog ownership is associated with improved physical activity and cardiovascular health.
Devarajan Rathish   +2 more
doaj   +1 more source

Identification of dysfunctional human–dog dyads through dog ownership histories

open access: yesOpen Veterinary Journal, 2019
The human-dog relationship is at least 16,000-years old and is mutually beneficial to both dyadic members. When the human-dog relationship becomes dysfunctional, however, there can be serious consequences for both parties and for society. Unfortunately, dysfunctional dyads are normally only identified after consequences have been felt (e.g., dog-human ...
Rute Canejo-Teixeira   +3 more
openaire   +5 more sources

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

open access: yesFEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro   +1 more
wiley   +1 more source

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

open access: yesFEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang   +10 more
wiley   +1 more source

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