Results 61 to 70 of about 629,087 (258)

The influence of dog ownership on objective measures of free-living physical activity and sedentary behaviour in community-dwelling older adults: a longitudinal case-controlled study

BMC Public Health, 2017
Background There is some evidence to suggest that dog ownership may improve physical activity (PA) among older adults, but to date, studies examining this, have either depended on self-report or incomplete datasets due to the type of activity monitor ...
Philippa Margaret Dall, Sarah Lesley Helen Ellis, Brian Martin Ellis, P Margaret Grant, Alison Colyer, Nancy Renee Gee, Malcolm Howard Granat, Daniel Simon Mills   +7 more
doaj   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

Threonine 348 regulates the subcellular localization of PTEN

FEBS Open Bio, EarlyView.
Thr348 in the C2 domain is a key contributor to PTEN subcellular localization. The PTEN350 fragment and PTENA4 accumulated in the nucleus, whereas PTENK13R,A4 predominantly localized to the plasma membrane. In contrast, substitution of Thr348 with Asp (T348D) disrupted these characteristic localization patterns, resulting in predominant cytoplasmic ...
Takashi Kato, Suzu Tanaka, Miyu Ohashi
wiley   +1 more source

Comparative mediation analysis of dog and cat ownership and perceived stress.

PLoS ONE
Companion animals, such as dogs and cats, are widely reported to be associated with lower stress, yet species-specific differences remain unclear. We conducted a comparative mediation analysis to examine how pet ownership type (dog vs.
Niwako Ogata, Anna L Heck, Hsin-Yi Weng
doaj   +1 more source

Associations between dog and cat ownership, social integration, mental health and physical activity: A cross-sectional study from the SCAPIS population

Human-Animal Interactions
Background: It is thought that pets have positive effects on psychosocial factors and physical activity. However, earlier findings are inconsistent. In this study, we investigated the link between dog/cat ownership and social integration, mental and ...
Catrin Henriksson, Mona-Lisa Wernroth, Gitiara Nasrin, Beatrice Kennedy, Tove Fall, Erik MG Olsson   +5 more
doaj   +1 more source

Sociodemographic correlates of prospective dog owners’ intentions to participate in controlled trials of dog ownership and human health

BMC Research Notes, 2018
Objective Dog ownership is popular, with research suggesting improvements in physical and psychological health of dog owners. However, majority of these studies were not investigator-controlled.
Debbie Chia, Lauren Powell, Vanessa Lee, Marjan Mosalman Haghighi, Anthony Podberscek, Ding Ding, Cathie Sherrington, Emmanuel Stamatakis   +7 more
doaj   +1 more source

Demography and determinants of dog and cat ownership in three towns of West Shoa zone, Oromia Region, Ethiopia

BMC Veterinary Research, 2020
Background The dog and cat population data is generally scarce in developing countries due to absence of surveys. The demography of owned dogs and cats, and the associated ownership characteristics, are essential for the control of pet population and ...
Endrias Zewdu Gebremedhin, Edilu Jorga Sarba, Abraham Mekebib Getaneh, Getachew Kebebew Tola, Solomon Shiferaw Endale, Lencho Megersa Marami   +5 more
doaj   +1 more source

Beta1 subunits enable fentanyl‐induced BK channel activation and opioid regulation of cerebral artery diameter

FEBS Open Bio, EarlyView.
During the current opioid crisis, the majority of overdose deaths are attributed to ultra‐potent synthetic opioids, such as fentanyl. While fentanyl exerts its action via opioid receptors, we propose that potassium channels in the brain blood vessels may also sense fentanyl.
Shiwani Thapa, Mohammed Nooh, Akhil Geddati, Alex Dopico, Anna N. Bukiya   +4 more
wiley   +1 more source

Risk of Non‐Arteritic Anterior Ischemic Optic Neuropathy in Idiopathic Intracranial Hypertension Patients Treated with GLP‐1 Receptor Agonists

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) have demonstrated significant weight‐reducing effects and may offer benefits in idiopathic intracranial hypertension (IIH); however, recent concerns about the risk of non‐arteritic anterior ischemic optic neuropathy (NAION) have emerged.
Faisal A. Al‐Harbi, Mohanad A. Alkuwaiti, Yazeed B. Alaql, Ahmed K. Alsaif, Ahmed A. Alessa, Meshari Ayed Alharbi, Mohammed Alfalah, Saud A. Alnaaim, Sajjad M. AlHaddad, Ahmed Y. Azzam   +9 more
wiley   +1 more source

Digital Cognitive Phenotyping for Differential Diagnosis and Monitoring in Neurological Conditions

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To assess the utility, accessibility, and equivalence to supervised scales of online cognitive assessment in older individuals with cognitive impairment. Methods Patients with Alzheimer's disease (AD, n = 31), idiopathic normal pressure hydrocephalus (iNPH, n = 26), and traumatic brain injury (TBI, n = 23) completed online cognitive ...
Martina Del Giovane, Valentina Giunchiglia, Michael C. B. David, Magdalena A. Kolanko, William R. Trender, Peter J. Hellyer, Harmeena Kaur, David J. Sharp, Christopher Carswell, Paresh A. Malhotra, Adam Hampshire   +10 more
wiley   +1 more source