Results 131 to 140 of about 1,551,991 (408)

Characterization of Microbial Dysbiosis and Metabolomic Changes in Dogs with Acute Diarrhea

PLoS ONE, 2015
Limited information is available regarding the metabolic consequences of intestinal dysbiosis in dogs with acute onset of diarrhea. The aim of this study was to evaluate the fecal microbiome, fecal concentrations of short-chain fatty acids (SCFAs), as ...
B. Guard, J. W. Barr, L. Reddivari, Cory Klemashevich, A. Jayaraman, J. Steiner, Jairam K. P. Vanamala, J. Suchodolski   +7 more
semanticscholar   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Clinical presentation, diagnostic findings and outcome of dogs with presumptive spinal-only meningoencephalomyelitis of unknown origin [PDF]

, 2017
Objectives: To summarise clinical presentation, diagnostic findings and long-term outcome for dogs clinically diagnosed with meningoencephalomyelitis of unknown origin affecting the spinal cord alone.
Cardy, Coates, Csebi, Da Costa, De Risio, Dewey, Eminaga, Fenn, Granger, Griffin, Meric, Parry, Scott, Tipold   +13 more
core   +2 more sources

Temporal Changes in Indicators of Testicular Dysgenesis Syndrome in Labrador and Golden Retrievers

Animals
Temporal changes in testicular traits have been reported in both humans and dogs. Analysis of % living sperm and motility from semen collections from 186 Labrador Retrievers and 113 Golden Retrievers between 2006 and 2023, and of incidents of ...
Thomas Lewis, Rachel Moxon, Gary C. W. England   +2 more
doaj   +1 more source

How size and genetic diversity shape lifespan across breeds of purebred dogs

, 2022
Cornelia Kraus, Noah Snyder‐Mackler, Daniel Promislow   +2 more
openalex   +2 more sources

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

Biomarkers of injury to neural tissue in veterinary medicine

Journal of Veterinary Research, 2016
There are numerous biomarkers of central and peripheral nervous system damage described in human and veterinary medicine. Many of these are already used as tools in the diagnosis of human neurological disorders, and many are investigated in regard to ...
Płonek Marta, Wrzosek Marcin, Nicpoń Józef   +2 more
doaj   +1 more source

Searching for ivermectin resistance in a Strongylidae population of horses stabled in Poland

BMC Veterinary Research, 2017
Background There are no available studies describing the possible resistance of strongyles to ivermectin in horses in Poland. One hundred seventy three horses from nine stud farms from South-Western Poland were studied.
A. Zak, N. Siwinska, M. Slowikowska, H. Borowicz, K. Kubiak, J. Hildebrand, M. Popiolek, A. Niedzwiedz   +7 more
doaj   +1 more source

Factors affecting the urinary aldosterone-to-creatinine ratio in healthy dogs and dogs with naturally occurring myxomatous mitral valve disease [PDF]

, 2021
Alberto Galizzi, Mara Bagardi, Angelica Stranieri, Anna Maria Zanaboni, Dario Malchiodi, V. Borromeo, Paola Brambilla, Chiara Locatelli   +7 more
openalex   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source