Results 111 to 120 of about 469,015 (313)

Efficacy and safety of the long-term oral administration of carprofen in the treatment of osteoarthritis in dogs [PDF]

, 2007
The aim of this study conducted in France was to confirm the efficacy and safety of the oral administration of carprofen (Rimadyl®) at 4 mg/kg once a day during four months in the treatment of clinically chronic osteoarthritis in dogs.
Autefage, André, Gosselin, Jacques
core  

Exploring the potential role of built environments in wildlife conservation during wildfires

Conservation Science and Practice
As the frequency and severity of wildfires continue to rise, fire refugia could play a critical role in reducing impacts on affected wildlife species.
Katrin Hohwieler, Carmen Piza Roca, Elizabeth Brunton, Michelle Ward, Romane H. Cristescu   +4 more
doaj   +1 more source

Supporting Families to ‘Make the Most’ of the Relationship Between Their Companion Dogs and Their Children with Autism Spectrum Condition: A Qualitative Exploration of the ‘Family Dog Service’

Behavioral Sciences
Evidence suggests that assistance and therapy dogs can positively impact the mental and physical health of children with autism spectrum condition (ASC) and their families. However, these services are often costly and inaccessible.
Emily Shoesmith, Heidi Stevens, Selina Gibsone, Cari Miles, Hannah Beal, Kelly Jennings, Elena Ratschen   +6 more
doaj   +1 more source

Canine Olfactory Thresholds to Amyl Acetate in a Biomedical Detection Scenario

Frontiers in Veterinary Science, 2019
Dogs' abilities to respond to concentrations of odorant molecules are generally deemed superior to electronic sensors. This sensitivity has been used traditionally in many areas; but is a more recent innovation within the medical field.
Astrid R. Concha, Astrid R. Concha, Claire M. Guest, Rob Harris, Thomas W. Pike, Alexandre Feugier, Helen Zulch, Helen Zulch, Daniel S. Mills   +8 more
doaj   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Age Is Just a Number: No Impacts of Scat Ageing on Single Nucleotide Polymorphism Genotyping Using a Target Capture Approach

Ecology and Evolution
Recent advances in DNA sequencing and genotyping technologies are rapidly building our capacity to address ecological, evolutionary, and conservation questions for wildlife. However, wildlife genetic research increasingly relies on samples containing low
Alexis L. Levengood, Katrin Hohwieler, Daniel Powell, Romane H. Cristescu   +3 more
doaj   +1 more source

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

FEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart, Manon Van den Abbeel, Christoph Schifflers, Karim Bouhjar, Andrea Scarmelotto, Alexis Khelfi, Anne‐Catherine Wera, Carine Michiels   +7 more
wiley   +1 more source

Maximising the Potential Benefit of Living with Companion Dogs for Autistic Children and Their Families: A Mixed-Methods Survey of the Impact of a Novel ‘Family Dog Service’

Animals
Background: Assistance dogs can support children with autism by improving emotional regulation and social functioning, but access is limited. The Family Dog Service was developed to help families of autistic children gain similar benefits through ...
Emily Shoesmith, Heidi Stevens, Selina Gibsone, Cari Miles, Hannah Beal, Kelly Jennings, Elena Ratschen   +6 more
doaj   +1 more source

The Dog Walkers

Ecozon@: European Journal of Literature, Culture and Environment, 2020
Images from series 'The Dog Walkers'.
openaire   +2 more sources

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source