Results 61 to 70 of about 1,190,922 (296)
Images from series 'The Dog Walkers'.
openaire +3 more sources
Comprehensive analysis of genomic mutations, gene expression, DNA methylation, and pathway analysis of TCGA data was carried out to define cancer types in which proteasome subunits expression is associated with worse survival. Albeit the effect of specific proteasome subunits on cellular function, the main role of the proteasome is better evaluated ...
Ruba Al‐Abdulla +5 more
wiley +1 more source
Preliminary Investigation of Food Guarding Behavior in Shelter Dogs in the United States [PDF]
Even though food guarding is an adaptive trait for dogs, they are often euthanized when they exhibit this behavior while at an animal shelter. This research demonstrates some dogs that guard their food can be adopted and guarding is seldom seen in the ...
Emily Weiss +2 more
core +2 more sources
mir‐196a promotes Esophagus Adenocarcinoma aggressiveness. On one hand, mir‐196a targets the valosin‐containing protein (VCP) mRNA, causing the accumulation of c‐MYC protein that leads to high amounts of TERT. On the other hand, mir‐196a targets the inhibitor of NFκB (NFKBIA).
Jesús García‐Castillo +8 more
wiley +1 more source
Signalment risk factors for cutaneous and renal glomerular vasculopathy (Alabama rot) in dogs in the UK [PDF]
Seasonal outbreaks of cutaneous and renal glomerular vasculopathy (CRGV) have been reported annually in UK dogs since 2012, yet the aetiology of the disease remains unknown. The objectives of this study were to explore whether any breeds had an increased
Cardwell, J M +5 more
core +2 more sources
Canine astroviruses appear to be widespread geographically. The prevalence may be significantly higher in pups with gastroenteric disease than in asymptomatic animals and virus shedding has been shown to correlate with gastroenteric signs in naturally infected dogs.
P. Moschidou +2 more
openaire +3 more sources
Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed +8 more
wiley +1 more source
The effect of Eck and reverse Eck fistula in dogs with experimental diabetes mellitus [PDF]
1. 1. Dogs with alloxan diabetes were subjected to Eck fistula. This procedure produced a marked increase in the amount of insulin necessary to control glycosuria.
Meyer, WH, Starzl, TE
core
Canine Trypanosoma cruzi infection in the Bolivian Chaco [PDF]
A cross-sectional study on Trypanosoma cruzi was carried out in 2013 to evaluate the role of dogs as possible source of infection for humans in two rural communities of the highly endemic Bolivian Chaco (Bartolo, Chuquisaca Department, n = 57 dogs; and ...
Bartoloni, Alessandro +9 more
core +2 more sources
Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma
GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski +19 more
wiley +1 more source

