Does canine inflammatory bowel disease influence gut microbial profile and host metabolism? [PDF]
Background: Inflammatory bowel disease (IBD) refers to a diverse group of chronic gastrointestinal diseases, and gut microbial dysbiosis has been proposed as a modulating factor in its pathogenesis.
Bosch, Guido +13 more
core +2 more sources
Function‐driven design of a surrogate interleukin‐2 receptor ligand
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
New Strategies of Canine Post-Adoption Support: Methods for a Prospective Longitudinal Cohort Study
In 2018, Dogs Trust (UK) launched the Post Adoption Support project, the largest known prospective cohort study investigating behavioural and health problems post-rehoming of dogs.
Emma L. Buckland +5 more
doaj +1 more source
Background Precise understanding of the dimensions of the vascular lumina is essential for accurate interpretation of cardiac vessels imaging. To the authors’ best knowledge, this is the first study focusing on the ultrasound measurement of the right ...
Natalia Siwinska +6 more
doaj +1 more source
Mechanisms of parasite‐mediated disruption of brain vessels
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
Serum symmetric dimethylarginine concentration in healthy horses and horses with acute kidney injury
Background There are limited options to diagnose acute kidney injury (AKI) in horses. Symmetric dimethylarginine (SDMA) is routinely used in human and small animal medicine.
Natalia Siwinska +4 more
doaj +1 more source
Signalment risk factors for cutaneous and renal glomerular vasculopathy (Alabama rot) in dogs in the UK [PDF]
Seasonal outbreaks of cutaneous and renal glomerular vasculopathy (CRGV) have been reported annually in UK dogs since 2012, yet the aetiology of the disease remains unknown. The objectives of this study were to explore whether any breeds had an increased
Cardwell, J M +5 more
core +2 more sources
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
UK Dog Owners’ Pre-Acquisition Information- and Advice-Seeking: A Mixed Methods Study
Dogs are the most common pet animal species in the UK. Little is known about information and advice gathering within the process of dog acquisition, nor what pre-acquisition research encompasses.
Rebecca Mead +4 more
doaj +1 more source
Canine lymphoma: a retrospective study (2009-2010) [PDF]
This study reviews the medical records of 56 dogs diagnosed with lymphoma based on the cytological and/or histological results between January 1, 2009 and December 31, 2010.
Daminet, Sylvie +3 more
core +1 more source

