Results 211 to 220 of about 1,208,109 (269)

Is AMP‐activated protein kinase activation a central mechanism of cardio‐metabolic outcomes after metabolic and bariatric surgery?

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
Abstract Metabolic and bariatric surgery (MBS) is the most effective treatment for severe obesity. It usually results in spectacular weight loss, associated with improvements of obesity‐associated comorbidities. The mechanisms underlying these benefits are not fully understood but could involve a postoperative activation of the enzyme 5′ AMP‐activated ...
Adrien Delcour, Nathalie Niederhoffer
wiley   +1 more source

Temporal variability in dissolved organic matter composition export in streams. [PDF]

open access: yesBiogeochemistry
Begum MS   +3 more
europepmc   +1 more source

Metformin attenuates metabolic insulin sensitivity and insulin‐stimulated carbohydrate oxidation after high‐intensity exercise training in adults at risk for metabolic syndrome

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
Abstract Aims Mixed evidence exists on whether metformin adds to or attenuates the insulin‐sensitising effects of exercise. To date, no studies have tested whether metformin differentially impacts exercise training intensity–mediated insulin sensitivity.
Steven K. Malin   +7 more
wiley   +1 more source

The depletion of serine beta‐lactamase‐like protein (LACTB) ameliorates metabolic dysfunction–associated steatotic liver disease by reducing ubiquitin‐mediated degradation of carnitine palmitoyltransferase 2

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
Abstract Aims Metabolic dysfunction–associated steatotic liver disease (MASLD) represents one of the most common chronic liver disorders worldwide, and its incidence continues to rise each year. Serine β‐lactamase‐like protein (LACTB) is a serine protease that plays a crucial role in lipid metabolism and hepatocellular carcinoma, but its function in ...
Wujiang Shi   +10 more
wiley   +1 more source

Fe-(μ-O)-Zn dual-atom boosting C-C coupling for direct oxidation of methane to acetic acid using O<sub>2</sub>. [PDF]

open access: yesNat Commun
Yu B   +12 more
europepmc   +1 more source

Effect of empagliflozin on urinary albumin excretion and hypoxic biomarkers in early diabetic kidney disease: A randomised double‐blind, placebo‐controlled trial

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
Abstract Aims The precise mechanism of sodium glucose co‐transporter 2 (SGLT2) inhibitor on reno‐protective effect has been still unclear. In this study, we hypothesised that SGLT2 inhibitor prevents diabetic kidney disease via reduction of hypoxia‐induced factors.
Hisashi Makino   +14 more
wiley   +1 more source

The spectrum of exogenous insulin requirement in people living with type 1 diabetes: A cross‐sectional analysis

open access: yes
Diabetes, Obesity and Metabolism, EarlyView.
Virginie Messier   +3 more
wiley   +1 more source

Comparison of pharmacodynamics and pharmacokinetics of ultra‐rapid‐acting insulin aspart and rapid‐acting insulin aspart around continuous moderate intensity exercise in adults with type 1 diabetes: A randomised controlled trial

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
Abstract Aims To compare the effects of dose reductions of ultra‐rapid‐acting insulin aspart (URA‐IAsp) and rapid‐acting insulin aspart (IAsp) on blood glucose concentrations during continuous moderate‐intensity exercise in people with type 1 diabetes (T1D).
Jason P. Pitt   +7 more
wiley   +1 more source

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