Results 91 to 100 of about 8,741,639 (312)

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Construction of a specialized terminology lexicon for coal mine safety

open access: yes上海师范大学学报. 自然科学版
To address issues such as insufficient terminology coverage and inadequate domain-specific lexicon construction in coal mine safety production, a method for constructing a specialized terminology database for coal mine safety production is proposed.
HUANG Tianchen, LIN Guoyuan
doaj   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Domain-Specific Expectations in Music Segmentation

open access: yesBrain Sciences, 2019
The acoustic cues that guide the assignment of phrase boundaries in music (pauses and pitch movements) overlap with those that are known for speech prosody.
Susana Silva   +2 more
doaj   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Domain-specific and domain-general predictors of math anxiety in adolescents and adults [PDF]

open access: yes
It is well-established that a negative relation exists between math anxiety (MA) and math performance. However, because there has been no systematic quantitative research on the predictors of MA, we conducted three studies in adolescents and adults to ...
Szczygieł, M., Hunt, T., Sarı, M. H.
core  

A Domain Specific Transformation Language

open access: yesCoRR, 2014
Domain specific languages (DSLs) allow domain experts to model parts of the system under development in a problem-oriented notation that is well-known in the respective domain. The introduction of a DSL is often accompanied the desire to transform its instances.
Bernhard Rumpe, Ingo Weisemöller
openaire   +2 more sources

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

LabelFlow Framework for Annotating Workflow Provenance

open access: yesInformatics, 2018
Scientists routinely analyse and share data for others to use. Successful data (re)use relies on having metadata describing the context of analysis of data. In many disciplines the creation of contextual metadata is referred to as reporting.
Pinar Alper   +3 more
doaj   +1 more source

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