Q#: Enabling scalable quantum computing and development with a high-level domain-specific language
Quantum computing exploits quantum phenomena such as superposition and entanglement to realize a form of parallelism that is not available to traditional computing.
Azariah, John +9 more
core +1 more source
Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley +1 more source
Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada +5 more
wiley +1 more source
Categorization of Unorganized Text Corpora for better Domain-Specific Language Modeling
This paper describes the process of categorization of unorganized text data gathered from the Internet to the in-domain and out-of-domain data for better domain-specific language modeling and speech recognition.
Jan Stas +3 more
doaj +1 more source
A Domain Specific Language for Expressing Model Matching [PDF]
National audienceA matching strategy computes mappings between two models by executing a set of heuristics. In this paper, we introduce the AtlanMod Matching Language (AML), a Domain Specific Language (DSL) for expressing matching strategies.
Bézivin, Jean +3 more
core +2 more sources
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman +4 more
wiley +1 more source
Unsupervised Cross-Domain Word Representation Learning
Meaning of a word varies from one domain to another. Despite this important domain dependence in word semantics, existing word representation learning methods are bound to a single domain.
Bollegala, Danushka +2 more
core +1 more source
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee +6 more
wiley +1 more source
Code Generation in Computational Neuroscience: A Review of Tools and Techniques
Advances in experimental techniques and computational power allowing researchers to gather anatomical and electrophysiological data at unprecedented levels of detail have fostered the development of increasingly complex models in computational ...
Inga Blundell +32 more
doaj +1 more source

