Results 61 to 70 of about 12,252,325 (244)

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

FEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

A DSL-Driven Solution and Code Generation for Accelerated Tourism Decision Support System Development

IEEE Access
Decision Support Systems (DSS) play a crucial role in commerce and tourism by assisting decision-making through data analysis, modeling, and visualization.
Adnane Souha, Charaf Ouaddi, Lamya Benaddi, Hamza Abdelmalek, El Mahi Bouziane, Abdeslam Jakimi   +5 more
doaj   +1 more source

Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus

FEBS Open Bio, EarlyView.
BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima, Gustavo Narvaes Guimarães, Emilyane de Oliveira Santana Amaral, Bianca Caroline Figueiredo Bianco, Manuel Jara‐Espejo, Sérgio Roberto Peres Line, Ana Paula de Souza, Aline Cristiane Planello   +7 more
wiley   +1 more source

A Domain-Specific Language and Simulation Architecture for the Oncilla Robot [PDF]

, 2013
Nordmann A, Tuleu A, Wrede S. A Domain-Specific Language and Simulation Architecture for the Oncilla Robot.
Wrede, Sebastian ; https://orcid.org/, Tuleu, Alexandre, Nordmann, Arne   +2 more
core  

HyMIR: A BI-Inspired Hybrid Intermediate Representation for Schema-Agnostic Text-to-SQL

IEEE Access
BIRD is a recent enterprise-scale Text-to-SQL benchmark that exposes a regime not covered by earlier datasets such as Spider: it consists of 95 real-world databases, which on average contain seven tables each, with abbreviated column names, dense foreign
Wei-Heng Chen, Ying-Ren Chien
doaj   +1 more source

Heterotropic regulation and negative homotropic cooperativity

FEBS Open Bio, EarlyView.
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea, Francesco Angelucci, Federica Arnesano, Gianmarco Pascarella, Patrizio Di Micco, Andrea Bellelli   +5 more
wiley   +1 more source

Language-specific neural dynamics extend syntax into the time domain

PLoS Biology
Studies of perception have long shown that the brain adds information to its sensory analysis of the physical environment. A touchstone example for humans is language use: to comprehend a physical signal like speech, the brain must add linguistic ...
Cas W. Coopmans, Helen de Hoop, Filiz Tezcan, Peter Hagoort, Andrea E. Martin   +4 more
doaj   +2 more sources

Modeling Atomic Structure & Behavior Through Electron Configurations

Atoms
Electron configurations are known to provide valuable insights into the electronic structure and behavior of atoms. They specify which and how the electronic (sub-) shells are occupied, and are thus an essential ingredient for most atomic observables ...
Stephan Fritzsche, Nishita M. Hosea, Houke Huang, Tianluo Luo, Aloka K. Sahoo   +4 more
doaj   +1 more source

Threonine 348 regulates the subcellular localization of PTEN

FEBS Open Bio, EarlyView.
Thr348 in the C2 domain is a key contributor to PTEN subcellular localization. The PTEN350 fragment and PTENA4 accumulated in the nucleus, whereas PTENK13R,A4 predominantly localized to the plasma membrane. In contrast, substitution of Thr348 with Asp (T348D) disrupted these characteristic localization patterns, resulting in predominant cytoplasmic ...
Takashi Kato, Suzu Tanaka, Miyu Ohashi
wiley   +1 more source

A Domain-Specific Language and Simulation Architecture for Motor Skill Exploration [PDF]

, 2013
Nordmann A, Tuleu A, Wrede S. A Domain-Specific Language and Simulation Architecture for Motor Skill Exploration.
Wrede, Sebastian ; https://orcid.org/, Tuleu, Alexandre, Nordmann, Arne   +2 more
core