Results 51 to 60 of about 1,532,627 (279)

MediBioDeBERTa: Biomedical Language Model With Continuous Learning and Intermediate Fine-Tuning

IEEE Access, 2023
The emergence of large language models (LLMs) has marked a significant milestone in the evolution of natural language processing. With the expanded use of LLMs in multiple fields, the development of domain-specific pre-trained language models (PLMs) has ...
Eunhui Kim, Yuna Jeong, Myung-Seok Choi
doaj   +1 more source

Defining Roles in Pediatric Palliative Care: Perspectives From Oncology and Palliative Care Teams

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Early integration of pediatric palliative care (PPC) is associated with improved symptom management, quality of life, and healthcare utilization for children with cancer. Despite this, variation persists in how PPC is understood, operationalized, and integrated within pediatric oncology programs. In particular, ambiguity surrounding
Leeat Granek, Lori Wiener, Stephanie Veldhuijzen van Zanten, Donna Johnston, Fyeza Hasan, Adam Rapoport, Nathasha Datoo, Kimberley Widger, Sumit Gupta, Karen Fergus, Anthony K. C. Chan, Alisha Kassam, Emily McCullogh, Dave Lysecki   +13 more
wiley   +1 more source

RETRIEVAL-AUGMENTED GENERATION USING DOMAIN-SPECIFIC TEXT: A PILOT STUDY

Journal of Engineering Science (Chişinău)
The natural language processing (NLP) field has witnessed remarkable advancements with the advent of large language models (LLMs) like GPT, Gemini, Claude, etc. These models are trained on vast amounts of text data, allowing
IAPĂSCURTĂ, Victor, KRONIN, Sergey, FIODOROV, Ion   +2 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Domain-Specific Language Model Pre-Training for Korean Tax Law Classification

IEEE Access, 2022
Owing to their increasing amendments and complexity, most taxpayers do not have the required knowledge of tax laws, which results in issues in everyday life.
Yeong Hyeon Gu, Xianghua Piao, Helin Yin, Dong Jin, Ri Zheng, Seong Joon Yoo   +5 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Phobos: A front-end approach to extensible compilers (long version) [PDF]

, 2002
This paper describes a practical approach for implementing certain types of domain-specific languages with extensible compilers. Given a compiler with one or more front-end languages, we introduce the idea of a "generic" front-end that allows the ...
Granicz, Adam, Hickey, Jason
core   +2 more sources

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

A DSL-Driven Solution and Code Generation for Accelerated Tourism Decision Support System Development

IEEE Access
Decision Support Systems (DSS) play a crucial role in commerce and tourism by assisting decision-making through data analysis, modeling, and visualization.
Adnane Souha, Charaf Ouaddi, Lamya Benaddi, Hamza Abdelmalek, El Mahi Bouziane, Abdeslam Jakimi   +5 more
doaj   +1 more source

Globalizing Domain-Specific Languages

, 2015
Dagstuhl Seminar 14412 Globalizing Domain-Specific Languages, Wadern, Germany, 5 Oct 2014 - 10 Oct 2014; Dagstuhl Reports 4(12), 32-50 (2015).
Combemale, Benoit, Cheng, Betty H.C., France, Robert B., Jézéquel, Jean-Marc, Rumpe, Bernhard   +4 more
  +6 more sources