Results 181 to 190 of about 3,849,410 (219)

Profiling of pollen in honey using multispectral imaging flow cytometry. [PDF]

NPJ Sci Food
Walther F, Hofmann M, Janke M, Erler S, Friedrich E, Treder M, Rakosy D, Harpole WS, Mäder P, Berdún A, Hornick T, Dunker S.   +11 more
europepmc   +1 more source

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

FEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen, Duc Trung Nguyen, Minyoung Cho, Jihun Kim, Soyeon In, Thai Uy Nguyen, Sunghoon Hurh, Beom Jin Park, Jong‐Ik Hwang   +8 more
wiley   +1 more source

DUF6383-domain containing protein from <i>Parabacteroides distasonis</i> predicts survival in patients with alcohol-associated hepatitis. [PDF]

Gut Microbes Rep
Kreimeyer H, Gonzalez C, Fondevila MF, AlcHepNet Investigators, Canbay A, Stärkel P, Gonzalez DJ, Schnabl B.   +7 more
europepmc   +1 more source

The C‐terminal domain of yeast Arginyltransferase1 is essential for its catalytic activity

FEBS Open Bio, EarlyView.
Arginyltransferase 1 (Ate1), a eukaryotic enzyme, catalyses arginylation, transferring arginine from tRNA‐Arg to the amino terminus of the target protein. Overexpression of Ate1 in yeast is lethal and is dependent on arginylation. This study elucidates how mutations in the cofactor‐binding and active site of Ate1 and truncation of its structural ...
Vikas Kumar Yadav, Shweta Shweta, Manisha Malhotra, Vikash Maurya, Akhilesh Kumar   +4 more
wiley   +1 more source

Naturalistic spatial education engages distinct neural processes for mental rotation, cognitive load, and linguistic demands. [PDF]

Proc Natl Acad Sci U S A
Gacetta EB, Laws ML, Aulet LS, Ozaydin TS, Tsay JS, Zapanta C, Cantlon JF.   +6 more
europepmc   +1 more source

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

FEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata, Yuxin Li, Kei Endo, Koichi Ito   +3 more
wiley   +1 more source

A split nozzle and two-protein chain-like fibers define the tail architecture of Pseudomonas aeruginosa podophage A1002. [PDF]

PLoS Biol
Pang H, Chen Y, Peng Z, Xiao H, Chen W, Li X, Chen P, Zheng J, Liu H.   +8 more
europepmc   +1 more source

Quality Indicators in End-of-Life Care for Children With Cancer in Low- and Middle-Income Countries. [PDF]

Cancer Med
McNeil MJ, Quintero XG, Salek M, Agulnik A, Downing J, Dussel V, Friedrich P, Garcia WG, Johnston EE, Movsisyan N, Namisango E, Rao K, Sansom-Daly UM, Widger K, Wiener L, Rodriguez-Galindo C, Baker JN.   +16 more
europepmc   +1 more source

Fine-Tuning Shifts Form Before Competence: Treatment-Correlated Style Drift Confounds Surface-Form Evaluation of Adapter Specialization. [PDF]

Entropy (Basel)
Benyoucef O, Dekhici L.
europepmc   +1 more source

Coccydynia as a Multimechanistic Pain Syndrome: A Narrative Synthesis and Proposal of the Coccyx Pain Phenotype Score (CPPS) for Mechanism-Based Clinical Phenotyping. [PDF]

J Pain Res
Khalfallah M, Savalli L, Khalfallah I, Bégué M.   +3 more
europepmc   +1 more source