Results 51 to 60 of about 803,494 (308)

Crystal structures of the human Dysferlin inner DysF domain [PDF]

, 2014
Background: Mutations in dysferlin, the first protein linked with the cell membrane repair mechanism, causes a group of muscular dystrophies called dysferlinopathies.
Cole, Ambrose R., Nicholas H Keep, Keep, Nicholas H., Altin Sula, Sula, Altin, Orengo, C., Ambrose R Cole, Corin Yeats, Yeats, C., Christine Orengo   +9 more
core   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

A unified and division-free CORDIC argument reduction method with unlimited convergence domain including inverse hyperbolic functions.

, 2022
S.1339 - 1344One of the main problems of the CORDIC algorithm is the limited convergence domain, in which the functions can be calculated. Two different approaches can be employed to overcome this constraint: first, an argument reduction method and ...
Hahn, H., Timmermann, D., Hosticka, B.J., Rix, B.   +3 more
core   +1 more source

Simultaneous reconstruction and denoising for DAS-VSP seismic data by RRU-net

Frontiers in Earth Science, 2023
Distributed acoustic sensing in vertical seismic profile (DAS-VSP) acquisition plays an important role in reservoir monitoring. But the field data can be noisy and associated with missing traces which affects the seismic imaging and geological ...
Huanhuan Tang, Shijun Cheng, Wuqun Li, Weijian Mao   +3 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Compact models for wireless systems [PDF]

, 2010
For the design and analysis of wireless systems, complex simulations are required and performed. Model order reduction techniques enable greater efficiencies to be achieved and concomitantly, a reduction in memory-resource usage. However, maintaining a
Condon, Marissa, Grahovski, Georgi G.
core  

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Research on Long-Tail Visual Recognition Technology with Edge-Side Domain Adaptation [PDF]

Jisuanji gongcheng
The deployment of deep learning models at the edge is hindered by challenges such as domain offset, long-tail distribution, and limited computing resources in the training data.
OUYANG Yuzhong, HAN Rui, LIU Chi
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Frequency domain iterative tuning for active noise and vibration control [PDF]

, 2008
In this thesis a new adaptive control method, called Iterative Tuning in the Frequency Domain (FD-IT), is proposed for Active Noise and Vibration Control (ANVC).
Luo, Jian
core