Results 181 to 190 of about 10,126,895 (308)

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

PSRNet: a phase-guided frequency-domain structure reconstruction network for RGB-T salient object detection. [PDF]

Front Neurorobot
Xie F, Zhou J, Gao F, Ma X, Yang C.
europepmc   +1 more source

The Distinctive Permutated Domain Structure of Periplasmic α-Amylase (MalS) from Glycoside Hydrolase Family 13 Subfamily 19. [PDF]

Molecules, 2023
An Y, Tran PL, Yoo MJ, Song HN, Park KH, Kim TJ, Park JT, Woo EJ.   +7 more
europepmc   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Domain Structure Transformation and Impedance Tuning in Partially Nanocrystallized Fe-Based Microwires. [PDF]

Sensors (Basel)
Aksenov O, Fuks A, Aronin A.
europepmc   +1 more source

High-Strength Heat-Elongated Thermoplastic Polyurethane Elastomer Consisting of a Stacked Domain Structure. [PDF]

Polymers (Basel), 2022
Takano M, Takamatsu K, Saito H.
europepmc   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

GluD1 at the synaptic crossroads: from domain structure to circuit dysfunction. [PDF]

Acta Pharmacol Sin
Chettiar PB, Dravid SM.
europepmc   +1 more source

Correction to: Distinct functions of FASCICLIN-LIKE ARABINOGALACTAN PROTEINS relate to domain structure. [PDF]

Plant Physiol, 2023
europepmc   +1 more source

Redox properties and PAS domain structure of the Escherichia coli energy sensor Aer indicate a multistate sensing mechanism. [PDF]

J Biol Chem, 2022
Maschmann ZA, Chua TK, Chandrasekaran S, Ibáñez H, Crane BR.   +4 more
europepmc   +1 more source