Results 171 to 180 of about 1,741,360 (267)

ANO5 p.I616F variant drives florid cemento-osseous dysplasia by disrupting transmembrane domain structure. [PDF]

BMC Oral Health
Zhang L, Jin W, Qin Y, Zhang Y, Qian Y, Li J, Liu Y, Shi Y, Xie R, Wang W.   +9 more
europepmc   +1 more source

Domain Structure, Thermal and Mechanical Properties of Polycaprolactone-Based Multiblock Polyurethane-Ureas under Control of Hard and Soft Segment Lengths. [PDF]

Polymers (Basel), 2022
Bugrov AN, Gorshkova YE, Ivan'kova EM, Kopitsa GP, Pavlova AA, Popova EN, Smirnova VE, Smyslov RY, Svetlichnyi VM, Vaganov GV, Vasil'ev BV.   +10 more
europepmc   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Insights into therapeutic discovery through the Kelch domain structure of Keap1 at ambient temperature. [PDF]

Turk J Biol
Yilmaz M, Sever B, Kutlu Y, Gül M, Okuducu C, Tavli S, Otsuka M, Fujita M, Haliloğlu T, Çiftçi H, Demirci H, Demirci H.   +11 more
europepmc   +1 more source

Heterologous DNA-prime/protein-boost immunization with a monomeric SARS-CoV-2 spike antigen redundantizes the trimeric receptor-binding domain structure to induce neutralizing antibodies in old mice. [PDF]

Front Immunol, 2023
Pflumm D, Seidel A, Klein F, Groß R, Krutzke L, Kochanek S, Kroschel J, Münch J, Stifter K, Schirmbeck R.   +9 more
europepmc   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Constructing a Broad-Pore-Domain Structure of Adsorbents for Acteoside Adsorption. [PDF]

Polymers (Basel)
Ru W, Liu J, Xiong F, Sun Y, Zhang Y, Li Y, Lv Y, Li X.   +7 more
europepmc   +1 more source

Genetic Insight into the Domain Structure and Functions of Dicer-Type Ribonucleases. [PDF]

Int J Mol Sci, 2021
Ciechanowska K, Pokornowska M, Kurzyńska-Kokorniak A.   +2 more
europepmc   +1 more source

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

FEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay, Junjie Xu, Josep Rizo   +2 more
wiley   +1 more source

Unraveling Desmin's Head Domain Structure and Function. [PDF]

Cells
Vlachakis D, Tsilafakis K, Kostavasili I, Kossida S, Mavroidis M.   +4 more
europepmc   +1 more source