A Simple Model of Protein Domain Swapping in Crowded Cellular Environments. [PDF]
Biophys J, 2016 Woodard JC, Dunatunga S, Shakhnovich EI.
europepmc +1 more source
Mass Spectrometry Structural Proteomics Enabled by Limited Proteolysis and Cross‐Linking
Mass Spectrometry Reviews, EarlyView.ABSTRACT The exploration of protein structure and function stands at the forefront of life science and represents an ever‐expanding focus in the development of proteomics. As mass spectrometry (MS) offers readout of protein conformational changes at both the protein and peptide levels, MS‐based structural proteomics is making significant strides in the
Haiyan Lu +4 more
wiley +1 more source
Small Molecule-Induced Domain Swapping as a Mechanism for Controlling Protein Function and Assembly. [PDF]
Sci Rep, 2017 Karchin JM +4 more
europepmc +1 more source
Fat/Water Separation at 7 T Using a 3D Radial Sequence With Quasi‐Continuous Echo Times
Magnetic Resonance in Medicine, EarlyView.ABSTRACT Purpose To achieve a reliable fat/water separation (FWS) at 7 T using a new 3D radial sequence and reconstruction workflow with quasi‐continuous TE sampling. Methods A 3D radial density‐adapted sequence with quasi‐continuous TE sampling was developed for a 7 T whole‐body MRI system.
Matthias Rohe +9 more
wiley +1 more source
Multi‐Agent Reinforcement Learning for Joint Police Patrol and Dispatch
Naval Research Logistics (NRL), EarlyView.ABSTRACT Police patrol units need to split their time between performing preventive patrol and being dispatched to serve emergency incidents. In the existing literature, patrol and dispatch decisions are often studied separately. We consider joint optimization of these two decisions to improve police operations efficiency and reduce response time to ...
Matthew Repasky, He Wang, Yao Xie
wiley +1 more source
Domain-Swapping Switch Point in Ste20 Protein Kinase SPAK. [PDF]
Biochemistry, 2015 Taylor CA +5 more
europepmc +1 more source
Crystal structure of the UBR-box from UBR6/FBXO11 reveals domain swapping mediated by zinc binding. [PDF]
Protein Sci, 2017 Muñoz-Escobar J, Kozlov G, Gehring K.
europepmc +1 more source
Balancing tracks and trees: Assessing railroad impact on Brazilian biodiversity
PLANTS, PEOPLE, PLANET, EarlyView.The Brazilian West–East Integration Railway (FIOL) aims to boost the national economy by improving commodity transport; however, it crosses three of Brazil's most biodiverse and fragile regions: the Caatinga, Cerrado and Atlantic Forest. Using digitised plant records and land‐use analyses, our study reveals significant vegetation loss within the ...
Ana Luiza Silva Rocha +3 more
wiley +1 more source
Proteins: Structure, Function, and Bioinformatics, EarlyView.ABSTRACT BorF is a short‐chain flavin reductase from a desert soil bacterium that uses NADH to reduce FAD to FADH2, which is used by the tryptophan‐6‐halogenase BorH to chlorinate tryptophan in the biosynthetic pathway of borregomycin A. The X‐ray crystal structure of BorF bound to FAD was solved to 2.37 Å by molecular replacement.
Zheng Ma +3 more
wiley +1 more source
Engineered Domain Swapping as an On/Off Switch for Protein Function. [PDF]
Chem Biol, 2015 Ha JH +4 more
europepmc +1 more source