Results 51 to 60 of about 270,111 (269)
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Succession of Weed Community on Wheat Lands in the Past 25 Years: A Case Study in Eastern China
BiologyWeeds represent increasingly troublesome threats to modern wheat production. Jiangsu Province, China, is one of the largest wheat-planting areas, characterized by a high level of agricultural mechanization, in the country.
Guoqi Chen +5 more
doaj +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
INHERITANCE OF CRUDE FAT AND RAW CELLULOSE IN GRAIN SORGHUM HYBRIDS F1
Зерновое хозяйство России, 2018 Grain sorghum is basically a forage crop, so a content of nutrients should be controlled during hybridization. Fat is a reserved substance which is considered to be a concentrated energetic and constructional force of a seed.
V. V. Kovtunov, O. A. Lushpina
doaj
BRICS Alliance: A SWOT Analysis and the Potential Implications for Ending the Dominance of the USD
BRICS Law JournalThe group known as BRICS, comprising Brazil, Russia, India, China, and South Africa, came into being when its members decided to join hands to challenge the economic and political power of the wealthier nations of North America and Western Europe and ...
A. Alrefai
doaj +1 more source
Frontiers in Psychology, 2017 The Affective Norms for Polish Short Texts (ANPST) dataset (Imbir, 2016d) is a list of 718 affective sentence stimuli with known affective properties with respect to subjectively perceived valence, arousal, dominance, origin, subjective significance, and
Kamil K. Imbir
doaj +1 more source
Rating the Dominance of Concepts in Semantic Taxonomies
Computers, 2022 The descriptive concepts of “semantic” taxonomies are assigned to content items of the publishing domain for supporting a plethora of operations, mostly regarding the organization and discoverability of the content, as well as for recommendation tasks ...
Gerasimos Razis +2 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Sparse Convolutional Neural Networks for Genome-Wide Prediction
Frontiers in Genetics, 2020 Genome-wide prediction (GWP) has become the state-of-the art method in artificial selection. Data sets often comprise number of genomic markers and individuals in ranges from a few thousands to millions.
Patrik Waldmann +2 more
doaj +1 more source