Results 71 to 80 of about 577,930 (304)
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Evolution Letters, 2020 Adaptation to contrasting environments occurs when advantageous alleles accumulate in each population, but it remains largely unknown whether these same advantageous alleles create genetic incompatibilities that can cause intrinsic reproductive isolation
Greg M. Walter +5 more
doaj +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
The concept of stochastic dominance is defined, and its relation to welfare, poverty, and income inequality explained. A brief discussion is provided of how statistical inference may be performed for hypotheses relating to stochastic dominance.
Russell Davidson
core
EcosphereAnts are one of the most widespread groups of insects, but the mechanisms allowing them to coexist despite having similar nutritional needs remain unclear.
Marie Bourel +4 more
doaj +1 more source
Total domination and least domination in a tree
Discrete Mathematics, 2003 A subset \(X\) of the vertex set \(V(G)\) of a graph \(G\) is called dominating (or total dominating) in \(G\), if for each \(x\in V(G)- X\) (or for each \(x\in V(G)\), respectively) there exists \(y\in X\) adjacent to \(x\). The least number of vertices of a dominating (or total dominating) set in \(G\) is the domination number \(\gamma(G)\) (or the ...
Xuezheng Lv, Jingzhong Mao
openaire +1 more source
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Dominance learning in diploid genetic algorithms for dynamic optimization problems [PDF]
, 2006 Copyright @ 2006 YangThis paper proposes an adaptive dominance mechanism for diploidy genetic algorithms in dynamic environments. In this scheme, the genotype to phenotype mapping in each gene locus is controlled by a dominance probability, which is ...
Yang, S +2 more
core +1 more source
Elitism and Stochastic Dominance [PDF]
Stochastic dominance has typically been used with a special emphasis on risk and inequality reduction something captured by the concavity of the utility function in the expected utility model.
Patrick Moyes, Stephen Bazen
core +2 more sources