Results 81 to 90 of about 552,137 (300)
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Generalized domination and efficient domination in graphs
Discrete Mathematics, 1996 The closed neighbourhood of a vertex \(v\) of a graph \(G\) is the set consisting of \(v\) and of all vertices adjacent to \(v\) in \(G\). A function \(f\) which maps the vertex set \(V(G)\) of \(G\) onto a subset \(Y\) of the set of real numbers is called \(Y\)-dominating in \(G\), if the sum of its values over the closed neighbourhood of each vertex \
David W. Bange +3 more
openaire +2 more sources
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
The concept of stochastic dominance is defined, and its relation to welfare, poverty, and income inequality explained. A brief discussion is provided of how statistical inference may be performed for hypotheses relating to stochastic dominance.
Russell Davidson
core
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Species richness, composition, and dominance of core and climate relicts of African miombo woodlands
EcosphereThe miombo woodlands, which span about 10% of the African continent, are essential for the ecosystem services they provide. These woodlands are mainly dominated by the genera Julbernardia, Isoberlinia, and Brachystegia.
Brenden Pienaar +3 more
doaj +1 more source
Total domination and least domination in a tree
Discrete Mathematics, 2003 A subset \(X\) of the vertex set \(V(G)\) of a graph \(G\) is called dominating (or total dominating) in \(G\), if for each \(x\in V(G)- X\) (or for each \(x\in V(G)\), respectively) there exists \(y\in X\) adjacent to \(x\). The least number of vertices of a dominating (or total dominating) set in \(G\) is the domination number \(\gamma(G)\) (or the ...
Xuezheng Lv, Jingzhong Mao
openaire +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Relating 2-rainbow domination to Roman domination
Discussiones Mathematicae Graph Theory, 2017 For a graph $G$, let $γ_R(G)$ and $γ_{r2}(G)$ denote the Roman domination number of $G$ and the $2$-rainbow domination number of $G$, respectively. It is known that $γ_{r2}(G)\leq γ_R(G)\leq \frac{3}{2}γ_{r2}(G)$. Fujita and Furuya (Difference between 2-rainbow domination and Roman domination in graphs, Discrete Applied Mathematics 161 (2013) 806-812 ...
Alvarado José D. +2 more
openaire +3 more sources
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source