Results 61 to 70 of about 577,930 (304)

Ranking Multi-Metric Scientific Achievements Using a Concept of Pareto Optimality

open access: yesMathematics, 2020
The ranking of multi-metric scientific achievements is a challenging task. For example, the scientific ranking of researchers utilizes two major types of indicators; namely, number of publications and citations.
Shahryar Rahnamayan   +3 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Applying abundance/biomass comparison curves to small mammals: a weak tool for detect urbanization-related stress in the assemblages?

open access: yesFolia Oecologica, 2020
Urbanization is a form of pervasive human-induced disturbance. We tested the effectiveness of Abundance/Biomass Comparisons (ABC) as an approach in detecting stress due to landscape urbanization in large small mammal assemblages obtained from pellets of ...
di Bagno Ermellina   +3 more
doaj   +1 more source

The compared costs of domination, location-domination and identification

open access: yesDiscussiones Mathematicae Graph Theory, 2020
Let \(G\) be a graph and \(\{u\in V(G):d_G(u,v)\leq r\}\) is a ball of radius \(r\in\mathbb{N}\) centered at \(v\in V(G)\) and denoted by \(B_r(v)\). We say that \(x,y\in V(G)\) are \(r\)-twins if \(B_r(x)=B_r(y)\). A set \(D_1\subseteq V(G)\) is an \(r\)-dominating code of \(G\) if \(D_1\cap B_r(v)\neq\emptyset\) for every \(v\in V(G)\).
Hudry, Olivier, Lobstein, Antoine
openaire   +3 more sources

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

On domination and independent domination numbers of a graph

open access: yesDiscrete Mathematics, 1978
AbstractFor a graph G, the definitions of domination number, denoted γ(G), and independent domination number, denoted i(G), are given, and the following results are obtained:Theorem. If G does not have an induced subgraph isomorphic to K1,3, then γ(G) = i(G).Corollary 1. For any graph G, γ(L(G))=i(L(G)), where L(G) is the line graph of G. (This extends
Robert B. Allan, Renu C. Laskar
openaire   +1 more source

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

Anthropogenic Impacts on Bark and Ambrosia Beetle Assemblages in Tropical Montane Forest in Northern Borneo

open access: yesInsects
Anthropogenic disturbances, such as forest conversion, have a profound impact on species distributions and biodiversity in tropical forests. This study aimed to determine the diversity and distribution of bark and ambrosia beetles (Curculionidae ...
Evahtira Gunggot   +7 more
doaj   +1 more source

Total domination versus paired domination [PDF]

open access: yesDiscussiones Mathematicae Graph Theory, 2012
A dominating set of a graph G is a vertex subset that any vertex of G either belongs to or is adjacent to. A total dominating set is a dominating set whose induced subgraph does not contain isolated vertices. The minimal size of a total dominating set, the total domination number, is denoted by t.
openaire   +1 more source

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