Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
A Notion of Semantic Coherence for Underspecified Semantic Representation [PDF]
The general problem of finding satisfying solutions to constraint-based underspecified representations of quantifier scope is NP-complete. Existing frameworks, including Dominance Graphs, Minimal Recursion Semantics, and Hole Semantics, have struggled to
Mehdi Manshadi +2 more
doaj +2 more sources
Vector dominance, one flavored baryons, and QCD domain walls from the "hidden" Wess-Zumino term
We further explore a recent proposal that the vector mesons in QCD have a special role as Chern-Simons fields on various QCD objects such as domain walls and the one flavored baryons.
Avner Karasik
doaj +1 more source
On the Transitive Domination Principle for Continuous Function-Kernels [PDF]
One of the interesting problems in the potential theory for a function-kernel is to investigate the relation between the domination principle and the balayage principle.
openaire +3 more sources
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
A Fiqhi and Legal Analysis of Unauthorized Encroachment on the Riverbed and Riparian Zone [PDF]
The issue of land occupation and water utilization is a vital matter that requires the establishment of specific regulations. Furthermore, according to Article 45 of the Iranian Constitution and Articles 1 and 2 of the Law on the Fair Distribution of ...
Alireza Ebrahimi, Reza Askari
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Discovering Design Principles From Dominated Solutions
Important progress has been made by many researchers in extracting fundamental design principles from patterns in design parameters along the nondominated front generated by evolutionary algorithms in biobjective optimization problems. However, to the best of our knowledge, no attention has been given to discovering design principles from the wealth of
Karim J. Chichakly, Margaret J. Eppstein
openaire +2 more sources
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
A consistent multidimensional Pigou-Dalton transfer principle. [PDF]
The Pigou-Dalton principle demands that a regressive transfer decreases social welfare. In the unidimensional setting this principle is consistent, because regressivity in terms of attribute amounts and regressivity in terms of individual well-being ...
Bosmans, Kristof +2 more
core +2 more sources

