Results 71 to 80 of about 1,326,337 (292)

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source

The basic postulates of the universal evolution model «Evolving matter» [PDF]

Философия и космология, 2015
The author reveals the features of construction of the universal evolution model, which he called «Evolving matter». According to the author, the material world, which is perceived in scales of the Earth and near space, consists of visually and ...
Bazaluk Oleg
doaj  

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

Molecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Artificial immune system based neural networks for solving multi-objective programming problems

Egyptian Informatics Journal, 2010
In this paper, a hybrid artificial intelligent approach based on the clonal selection principle of artificial immune system (AIS) and neural networks is proposed to solve multi-objective programming problems.
Waiel F. Abd El-Wahed, Elsayed M. Zaki, Adel M. El-Refaey   +2 more
doaj   +1 more source

STOCHASTIC DOMINANCE [PDF]

The concept of stochastic dominance is defined, and its relation to welfare, poverty, and income inequality explained. A brief discussion is provided of how statistical inference may be performed for hypotheses relating to stochastic dominance.
Russell Davidson
core  

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Ant-based extraction of rules in simple decision systems over ontological graphs

International Journal of Applied Mathematics and Computer Science, 2015
In the paper, the problem of extraction of complex decision rules in simple decision systems over ontological graphs is considered. The extracted rules are consistent with the dominance principle similar to that applied in the dominancebased rough set ...
Pancerz Krzysztof, Lewicki Arkadiusz, Tadeusiewicz Ryszard   +2 more
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Competition law and corporate social responsibility: a review of the special responsibility of dominant firms in competition law

De Jure, 2020
SUMMARY “with great power, comes great responsibility”1 Few concepts aptly captures competition law’s expectations on firms with substantial market share or market power than ‘with great power, comes great responsibility’, made popular in American ...
Phumudzo S. Munyai
doaj