Results 111 to 120 of about 2,400,064 (330)

Establishment of a coculture system for Porphyromonas gingivalis and head and neck squamous cell carcinoma using spheroid culture and LATS inhibition

open access: yesFEBS Open Bio, EarlyView.
We established a spheroid coculture system enabling viable Porphyromonas gingivalis–HNSCC interactions under normoxic conditions. Inhibition of LATS1/2 maintains tumor cells in an undifferentiated state, which may promote spheroid growth and create a more permissive environment for bacterial persistence.
Yurika Nakajima   +4 more
wiley   +1 more source

The LDP at 50: The Rise, Power Resources, and Perspectives of Japan’s Dominant Party [PDF]

open access: yes
Japan’s ruling party is a prime example of a dominant party. While dominant parties in other democracies around the world have lost their grip on power or have even disappeared altogether, the LDP is still going strong.
Patrick Köllner
core  

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

open access: yesFEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig   +7 more
wiley   +1 more source

Search Design Policy, Digital Disruption and Competition Law

open access: yesMarket and Competition Law Review, 2017
It is debatable whether traditional competition law tools and remedies are able to deal with the digital disruption and whether it is desirable to adjust or even replace categories that have proven to be mainly suited to tackle anticompetitive conducts ...
Valeria Falce, Massimiliano Granieri
doaj   +1 more source

Dominated Estimates of Positive Contractions [PDF]

open access: yesProceedings of the American Mathematical Society, 1969
Chacon, R. V., Olsen, J.
openaire   +2 more sources

Down‐regulation of Shh in the hair follicles of mice during chemotherapy‐induced hair loss is mediated by the JAK/STAT1 signaling pathway

open access: yesFEBS Open Bio, EarlyView.
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan   +6 more
wiley   +1 more source

A Note on Market Power in an Emission Permits Market with Banking [PDF]

open access: yes
In this paper, we investigate the effect of market power on the equilibrium path of an emission permits market in which firms can bank current permits for use in later periods.
Juan-Pablo Montero, Matti Liski
core  

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

open access: yesFEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl   +13 more
wiley   +1 more source

COLLECTIVE DOMINATION IN THE MARKET

open access: yesPravo, 2009
Antimonopoly law in its provisions prohibiting cartel agreements primarily have in mind more joint activities of economic entities, while the prohibition of abuse of dominant position is reserved for the individual action of dominant companies.
Sanja Škorić
doaj  

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