Results 61 to 70 of about 2,400,064 (330)
Assessment of shoulder active range of motion in prone versus supine:A reliability and concurrent validity study [PDF]
, 2015 Background: As swimming and surfing are prone dominant sports, it would be more sport specific to assess shoulder active range of motion in this position.
Abbott, Allan +4 more
core +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
A Spatial Characterization of the Sagittarius Dwarf Galaxy Tidal Tails [PDF]
, 2013 We measure the spatial density of F turnoff stars in the Sagittarius dwarf tidal stream, from Sloan Digital Sky Survey (SDSS) data, using statistical photometric parallax.
Cole, Nathan +8 more
core +3 more sources
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
FACILIDADES ESENCIALES Y ABUSO DE POSICIÓN DOMINANTE
Revista de Derecho (Coquimbo)El presente trabajo describe la situación actual del desarrollo y avance tanto doctrinal como jurisprudencial del derecho de la libre competencia, respecto de la institución de las facilidades esenciales y el abuso de posición dominante que realizan ...
ALFREDO UGARTE SOTO
doaj +1 more source
Vol. 2011, 4(4)The Autonomy of Sector-Specific Regulation – Is It Still Worth Protecting? Further Thoughts on the Parallel Application ofCompetition Law and Regulatory Instruments [PDF]
Yearbook of Antitrust and Regulatory Studies, 2011 This article sets out to contribute to the on-going discussion regarding the relationship between competition law and sector-specific regulation, as well as the parallel application of competition law and regulatory instruments.
Aleksander Stawicki
doaj
International Journal of Sports Physical Therapy, 2021 # Background Many studies have been done on the strength and mobility of the shoulder and hip in baseball players, but fewer studies have examined these metrics in softball players.
Cameron R Guy +4 more
doaj +1 more source