Results 81 to 90 of about 480,644 (302)
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Selçuk Üniversitesi Sosyal Bilimler Enstitüsü Dergisi, 2015 Ekonomi biliminin gelişimi ile gözlemlenen en önemli olgu, piyasa ekonomisinde oluşacak çeşitli aksaklıkların, ekonominin temelini oluşturan serbest rekabet ortamını bozabilecek olmasıdır.
Dilek Karaman
doaj
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Special liability of businesses in dominant position
, 2016 Title: Special responsibility of undertaking in dominant position Author: Iva Čechráková Department: Department of Business Law Supervisor: JUDr. Daniel Patěk, Ph.D Abstract: This thesis deals with the doctrine of special responsibility of the dominant ...
Čechráková, Iva
core
THE ABUSE OF DOMINANT POSITION - RESTRICTING COMPETITION PRACTICE. CASE STUDY: ENI [PDF]
Annals of the University of Oradea: Economic Science, 2013 The abuse of dominant position along with cartel, merger and state aid are practices restricting competition strictly regulated at EU level. These practices can have a disastrous effect on the internal market harming both competition especially consumers.
BERINDE Mihai, FORA Andreea-Florina
doaj
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Collective dominant position in EC competition law
, 2010 Pored postojanja individualne dominacije, moguće je da se dve ili više kompanija nađu u kolektivnom dominantnom položaju. O tome svedoči i sam član 82. Ugovora o EZ koji se odnosi na zloupotrebu dominantnog položaja od strane 'jednog ili više preduzeća'.
Domazet, Siniša
core
Fidelity rebates and Aase of dominant position
, 2017 Διπλωματική εργασία - Πάντειο Πανεπιστήμιο. Τμήμα Διεθνών, Ευρωπαϊκών και Περιφερειακών Σπουδών, ΠΜΣ, κατεύθυνση Ευρωπαϊκό Δίκαιο και Πολιτική, 2017Βιβλιογραφία: σ. 84-92Η εξέταση των εκπτώσεων πίστεως και της κατάχρησης δεσπόζουσας θέσης σε συνδυασμό με
Σιδέρη Κωνσταντίνα Ε.
core +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source