Results 91 to 100 of about 53,392 (268)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

When Sets Are Not Sum-dominant

open access: yesJ. Integer Seq., 2019
16 pages, published in J.
openaire   +4 more sources

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Independent set dominating sets in bipartite graphs [PDF]

open access: yesOpuscula Mathematica, 2005
The paper continues the study of independent set dominating sets in graphs which was started by E. Sampathkumar. A subset \(D\) of the vertex set \(V(G)\) of a graph \(G\) is called a set dominating set (shortly sd-set) in \(G\), if for each set \(X ...
Bohdan Zelinka
doaj  

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Dominating Set Algorithms for Wireless Sensor Networks Survivability

open access: yesIEEE Access, 2018
Limited energy of the sensors is one of the key issues towards realizing a reliable wireless sensor network (WSN), which can survive under the emerging WSN applications.
Tayler Pino   +2 more
doaj   +1 more source

Dominating Sets and Local Treewidth

open access: yes, 2003
It is known that the treewidth of a planar graph with a dominating set of size d is O(sqrt{d}) and this fact is used as the basis for several fixed parameter algorithms on planar graphs. An interesting question motivating our study is if similar bounds can be obtained for larger minor closed graph families.
Thilikos Touloupas, Dimitrios   +1 more
openaire   +2 more sources

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