Results 81 to 90 of about 490,847 (283)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

On the number of minimum dominating sets and total dominating sets in forests

Journal of Graph Theory
AbstractWe show that the maximum number of minimum dominating sets of a forest with domination number is at most and construct for each a tree with domination number that has more than minimum dominating sets. Furthermore, we disprove a conjecture about the number of minimum total dominating sets in forests by Henning, Mohr and Rautenbach.
Jan Petr, Julien Portier, Leo Versteegen
openaire   +4 more sources

Chemical Reaction Optimization for Minimum Weight Dominating Set

Applied Computational Intelligence and Soft Computing, 2023
Dominating set of a graph can be defined as the set of vertices that can cover all other vertices of the graph. The minimum weight dominating set (MWDS) is the minimum number of vertices in the dominating set with minimum total weight.
A. Pritam Khan Boni, B. Md. Rafiqul Islam   +1 more
doaj   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Partitioning a graph into a dominating set, a total dominating set, and something else [PDF]

Discussiones Mathematicae Graph Theory, 2010
A recent result of Henning and Southey (A note on graphs with disjoint dominating and total dominating set, {\it Ars Comb.} {\bf 89} (2008), 159--162) implies that every connected graph of minimum degree at least three has a dominating set $D$ and a total dominating set $T$ which are disjoint.
Michael A. Henning, Christian Löwenstein, Dieter Rautenbach   +2 more
openaire   +1 more source

The Directed Dominating Set Problem: Generalized Leaf Removal and Belief Propagation

, 2015
A minimum dominating set for a digraph (directed graph) is a smallest set of vertices such that each vertex either belongs to this set or has at least one parent vertex in this set. We solve this hard combinatorial optimization problem approximately by a
C Pang, F Molnár Jr, FR Kschischang, G Gutin, HJ Zhou, J Leskovec, JH Zhao, JQ Xiao, M Bauer, M Garey, M Mézard, M Mézard, M Mézard, M Richardson, M Ripeanu, S Wuchty, T Takaguchi, TW Haynes, Y Fu, Y Yang, YY Liu, YY Liu   +21 more
core   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Independent point-set dominating sets in graphs

AKCE International Journal of Graphs and Combinatorics, 2020
In this paper, we study graphs which possess an independent point-set dominating set (in short, ipsd-set). We call such a graph as an ipsd-graph. We first provide general structural characterization of separable ipsd-graphs and thereafter, in our quest ...
Purnima Gupta, Alka Goyal, Ranjana Jain
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source