Results 111 to 120 of about 623,562 (309)
A Conversation with Archbishop Desmond Tutu: Leaders Transforming Cultures
Riane Eisler talks with Nobel laureate Archbishop Desmond Tutu about transforming cultures from domination to partnership and progress in this direction, including changing traditions of violence against women and children, gender equality, and the role ...
Riane Eisler
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Anaplastic thyroid cancer (ATC) lacks iodide uptake ability due to MAPK activation increasing the expression of the histone methyltransferase EZH2, which represses thyroid differentiation genes (TDGs) such as the sodium iodide symporter (NIS). Dual inhibition of MAPK (U0126) and EZH2 (EPZ6438/Tazemetostat) reverses this mechanism, thus restoring TDG ...
Diego Claro de Mello +6 more
wiley +1 more source
Theories and Dimensions of Algorithmic Power, between Agency and Domination
This article reviews the critical and sociological literature on algorithms and AI in light of anthropocentric social theories of power and its dimensions.
Massimo Airoldi
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There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes +20 more
wiley +1 more source
Building a Sustainable Society: The Necessity to Change the Term 'Consumer'
The profit-seeking system leads to many negative environmental impacts. Within this economic system, consumption reflects an important relationship between humans and nature.
Sabrina Chakori
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This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani +14 more
wiley +1 more source
Cuerpo, sexualidad y violencia simbólica en la tortura sexual
This article is an approach to the phenomenon of torture, particularly sexual torture, and it aims to inquire into the common interpretative frameworks that are constructed in the sexual torture exerted over the individual bodies, as metaphorical ...
Natalia Rodríguez Grisales
doaj +1 more source
mir‐196a promotes Esophagus Adenocarcinoma aggressiveness. On one hand, mir‐196a targets the valosin‐containing protein (VCP) mRNA, causing the accumulation of c‐MYC protein that leads to high amounts of TERT. On the other hand, mir‐196a targets the inhibitor of NFκB (NFKBIA).
Jesús García‐Castillo +8 more
wiley +1 more source
The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine +10 more
wiley +1 more source
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Henda C. Swart +2 more
openaire +2 more sources

