Results 61 to 70 of about 44,708 (295)

Dimensions of Emancipation: Rethinking Subjectivity, Domination and Temporality in Feminist Theory

Redescriptions, 2016
“Emancipation” is one of the most opaque words in political language and political theory. It refers to the hope of overcoming all forms of domination, yet is articulated with the highly ambivalent notions of reason, progress, equality and liberty, and ...
Susanne Lettow
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Roadmap to a Caring Economics: Beyond Capitalism and Socialism

Interdisciplinary Journal of Partnership Studies, 2017
Our unprecedented technological, economic, and environmental challenges call for thinking that goes beyond capitalism and socialism, both of which were developed in early industrial times.
Riane Eisler
doaj   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

FEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

From Domination to a Caring Ecology: Healing Paradigms and Creative Practices for the Apprenticene

Interdisciplinary Journal of Partnership Studies, 2017
This article explores, in four main sections, the idea of designing and applying human-environment paradigms. First, Caring Ecology criteria for human-environment paradigms are proposed that combine the principles of caring in Partnership Studies, with ...
Jonee Kulman Brigham
doaj   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

This is a Man’s world : autorité et pouvoir genrés dans le milieu des banques centrales

Revue de la Régulation, 2019
This article deals with the issue of gender in central banks. The latter are characterized by male domination, since there are still few women as chairpersons or exerting a high-ranked status within central banks. Resting on qualitative methods involving
Guillaume Vallet
doaj   +1 more source

Hereditary equality of domination and exponential domination

Discussiones Mathematicae Graph Theory, 2018
We characterize a large subclass of the class of those graphs $G$ for which the exponential domination number of $H$ equals the domination number of $H$ for every induced subgraph $H$ of $G$.
Henning Michael A., Jäger Simon, Rautenbach Dieter   +2 more
openaire   +4 more sources