Results 81 to 90 of about 423,913 (277)

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

open access: yesMolecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes   +20 more
wiley   +1 more source

DOMINATION AND CAPITALIST STATE

open access: yesRa Ximhai, 2018
The present constitutes a reflective analysis of the theory that for decades has described the mechanisms used by the capitalist state to exercise its domination in the world system.
Diana Morin-López
doaj  

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

open access: yesMolecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani   +14 more
wiley   +1 more source

Forum on Recognition in Foreign Policy (Analysis) and (The Study of) Diplomacy [PDF]

open access: yesContexto Internacional
What if the quest for recognition, not power, rank or security, were the overriding objective of foreign policies? What if practices of recognition both empower and subjugate by fixing identities and reproducing the terms upon which agents become ...
Stefano Guzzini   +2 more
doaj   +1 more source

MicroRNA 196a contributes to the aggressiveness of esophageal adenocarcinoma through the MYC/TERT/NFκB axis

open access: yesMolecular Oncology, EarlyView.
mir‐196a promotes Esophagus Adenocarcinoma aggressiveness. On one hand, mir‐196a targets the valosin‐containing protein (VCP) mRNA, causing the accumulation of c‐MYC protein that leads to high amounts of TERT. On the other hand, mir‐196a targets the inhibitor of NFκB (NFKBIA).
Jesús García‐Castillo   +8 more
wiley   +1 more source

Human Possibilities: The Interaction of Biology and Culture

open access: yesInterdisciplinary Journal of Partnership Studies, 2015
This article briefly describes the two main strands of a new unified theory about human nature and human possibilities: cultural transformation theory and bio-culturalism.
Riane Eisler
doaj   +1 more source

Dominating sets and ego-centered decompositions in social networks

open access: yes, 2016
Our aim here is to address the problem of decomposing a whole network into a minimal number of ego-centered subnetworks. For this purpose, the network egos are picked out as the members of a minimum dominating set of the network. However, to find such an
Boudourides, Moses A., Lenis, Sergios T.
core   +1 more source

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