Results 81 to 90 of about 22,912,690 (329)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Explication sociologique et domination sociale

open access: yesSociologies, 2012
The domination is a central concept of the sociological analysis. To such a point that a sociology of the domination made the key word of its explanations.
Michel Messu
doaj  

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

La dimension spatiale du travail des livreurs des plateformes

open access: yesCarnets de Géographes, 2023
From a research based on interviews and non-participant observation, this article proposes an analysis of the spatial dimension of plateforms delivery men’s work (UberEats, Deliveroo), based on the case of Nantes metropolis.
Claire Burban
doaj  

From Domination to Autonomy: Two Eras of Progress in World-sociological Perspective

open access: yesHistoricka Sociologie, 2015
In recent decades, the belief in progress that was widespread across the two centuries following the French Revolution has withered away. This article suggests, though, that the diagnosis of the end of progress can be used as an occasion to rethink what ...
Peter Wagner
doaj   +1 more source

Humpty Dumpty domination on correlational data analysis in social welfare researches [PDF]

open access: yesفصلنامه رفاه اجتماعی, 2023
Introduction Identifying and correct errors is essential to science, so propose the maxim that science is self correcting. While the err is humain is accepted reflected in philosophy of science especially in giving rise to the maxim that scientific ...
hamidreza oreyzi
doaj  

Meritocracy, social mobility and a new form of class domination

open access: yesBritish Journal of Sociology of Education, 2019
Meritocracy is used by governments in many societies as an ‘effective’ way to represent social justice and legitimise – explain away – class inequality.
Jin Jin, S. Ball
semanticscholar   +1 more source

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

Cell density–dependent nuclear‐cytoplasmic shuttling of SETDB1 integrates with Hippo signaling to regulate YAP1‐mediated transcription

open access: yesFEBS Letters, EarlyView.
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom   +3 more
wiley   +1 more source

Does a Mugger Dominate? Episodic Power and the Structural Dimension of Domination

open access: yesThe Journal of Political Philosophy, 2019
IMAGINE you are walking through a park in the twilight. Suddenly, a mugger points a gun at you, threatening to shoot you if you do not hand over your valuables. Is this an instance of domination?
Dorothea Gädeke
semanticscholar   +1 more source

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