Results 71 to 80 of about 6,252 (211)

Renal toxicity of domoic acid

The FASEB Journal, 2013
Domoic acid (DA) is a glutamate analog and a characterized neurotoxicant. Outside of the CNS, glutamate receptors are also found in peripheral tissues, including the kidney, which opens the possibility that the kidney may also be susceptible to excitatory toxicity.
Jason A Funk, Michael G Janech, Stacy L Steele, Joshua C Dillon, P Darwin Bell   +4 more
openaire   +1 more source

Ischemic Cardiomyopathy Following Seizure Induction by Domoic Acid [PDF]

The American Journal of Pathology, 2011
Exposure to the excitotoxin domoic acid (DOM) has been shown to produce cardiac lesions in both clinical and animal studies. We have previously shown that DOM failed to directly affect cardiomyocyte viability and energetics, but the development of this cardiomyopathy has remained unexplained.
Alexandra, Vranyac-Tramoundanas, Joanne C, Harrison, Punam M, Sawant, D Steven, Kerr, Ivan A, Sammut   +4 more
openaire   +2 more sources

Plankton communities today and tomorrow—potential impacts of multiple global change drivers and marine heatwaves

Limnology and Oceanography, Volume 70, Issue S2, Page S225-S241, December 2025.
Abstract In the context of global change, marine organisms are subjected not only to gradual changes in abiotic parameters, but also to an increasing number of extreme events, such as heatwaves. However, we still know little about the influence of heatwaves on the structure of marine communities, and experimental studies are needed to test the impact ...
Cédric L. Meunier, Josefin Schmidt, Antonia Ahme, Areti Balkoni, Katharina Berg, Lea Blum, Maarten Boersma, Jan D. Brüwer, Bernhard M. Fuchs, Luis Gimenez, Maïté Guignard, Ruben Schulte‐Hillen, Bernd Krock, Johannes Rick, Herwig Stibor, Maria Stockenreiter, Simon Tulatz, Felix Weber, Antje Wichels, Karen Helen Wiltshire, Sylke Wohlrab, Inga V. Kirstein   +21 more
wiley   +1 more source

Grazer‐induced bioluminescence and toxicity in marine dinoflagellates

Limnology and Oceanography, Volume 70, Issue 12, Page 3769-3783, December 2025.
Abstract Marine copepods are the most abundant multicellular zooplankton in the global oceans. They imprint their surrounding waters with a unique bouquet of chemical compounds, including polar lipids such as copepodamides. Prey organisms can detect copepodamides and respond by inducing defensive traits including bioluminescence, toxin production ...
Paula Gonzalo‐Valmala, Milad Pourdanandeh, Sandra Lage, Erik Selander   +3 more
wiley   +1 more source

In situ monitoring of toxic effects of algal toxin on cells by a novel microfluidic flow cytometry instrument

Ecotoxicology and Environmental Safety
Algal toxins produced by microalgae, such as domoic acid (DA)11 (DA) domoic acid, have toxic effects on humans. However, toxicity tests using mice only yield lethal doses of algal toxins without providing insights into the mechanism of action on cells ...
Yuezhu Wang, Yichi Zhang, Junsheng Wang, Weibing Liu, Huan Wang, Mingzhu Song, Hongyue Zhang, Xin Wang   +7 more
doaj   +1 more source

Harmful algal blooms and climate change: exploring future distribution changes [PDF]

, 2018
Harmful algae can cause death in fish, shellfish, marine mammals, and humans, via their toxins or from effects associated with their sheer quantity. There are many species, which cause a variety of problems around north-west Europe, and the frequency and
Anderson, Anderson, Anderson, Artioli, Barnes, Barton, Bell, Berdalet, Bill, Bresnan, Bryony L Townhill, Cheung, Cheung, W. W. L., Lam, V. W. Y., Sarmiento, J. L., Kearney, K., Watson, R., and Pauly, Clarke, Collins, Cusack, Davidson, Davidson, Davidson, Dunne, Elith, Elizabeth Bear, Flores-Moya, Glibert, Gobler, Gordon, Hall-Spencer, Hallegraef, Hannah, Henson, Hinder, Hinder, Hoagland, Hobday, Holt, Holt, IPCC, John K Pinnegar, Jonathan Tinker, Jones, Jones, Kaschner, Kibler, Kudela, Lewitus, Marques, McGillicuddy, Mercks, B., Steyaert, M., Vanreusel, A., Vincx, M., and Vanaverbeke, Miranda Jones, Moore, Moore, Moore, Phillips, Pope, Python Software Foundation, Ready, Reiss, Reiss, Rubao Ji, Rutterford, Smith, Smithsonian, Sophie Pitois, Stephen D Simpson, Stephen Dye, Tatters, Thomson, Tinker, Tinker, Townhill, Valiela, van der Molen, Veronique Creach, Vierod, Weinert, Wells, Wise, Woods Hole Oceanographic Institute, WoRMS, WoRMS, WoRMS, WoRMS   +81 more
core   +1 more source

Intraguild predation in sympatric seals and the effect on a declining population

Journal of Animal Ecology, Volume 94, Issue 12, Page 2572-2583, December 2025.
This study examined the prevalence, spatial extent, and temporal trends of grey seal intraguild predation (IGP). We demonstrated the utility of integrating disparate datasets to address conservation challenges and highlighted how IGP, while seemingly rare, can hold sympatric species in a predator‐pit and in small populations may contribute to declines.
Izzy Langley, Andrew Brownlow, Debbie J. F. Russell   +2 more
wiley   +1 more source

The Concise Guide to PHARMACOLOGY 2025/26: Ion channels

British Journal of Pharmacology, Volume 182, Issue S1, Page S152-S241, December 2025.
The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,
Stephen P. H. Alexander, Jörg Striessnig, Alasdair J. Gibb, Alistair A. Mathie, Emma L. Veale, Eamonn Kelly, Chloe J. Peach, Jane F. Armstrong, Elena Faccenda, Simon D. Harding, Christopher Southan, Jamie A. Davies, Richard W. Aldrich, Bernard Attali, Austin M. Baggetta, Elvir Becirovic, David J. Beech, Martin Biel, Roslyn M. Bill, Ana I. Caceres, William A. Catterall, Han Chow Chua, Alex C. Conner, Henry Danahay, Paul Davies, Katrien De Clerq, Markus Delling, Francesco Di Virgilio, Simonetta Falzoni, Wei Fang, Stefanie Fenske, Anna Fortuny‐Gomez, Samuel Fountain, George K. Chandy, Mohammad‐Reza Ghovanloo, Steve A. N. Goldstein, Martin Gosling, Christian Grimm, Stephan Grissmer, Kotdaji Ha, Tim G. Hales, Verena Hammelmann, Israel Hanukoglu, Meiqin Hu, Ad P. Ijzerman, Sairam V. Jabba, Mike Jarvis, Anders A. Jensen, Sven E. Jordt, Leonard K. Kaczmarek, Stephan Kellenberger, Charles Kennedy, Brian King, Philip Kitchen, Qiang Liu, Joseph W. Lynch, Rian W. Manville, Jessica Meades, Verena Mehlfeld, Annette Nicke, Stefan Offermanns, Edward Pérez‐Reyes, Leigh D. Plant, Stephan A. Pless, Lachlan D. Rash, Dejian Ren, Hussein N. Rubaiy, Mootaz M. Salman, Werner Sieghart, Lucia G. Sivilotti, Trevor G. Smart, Terrance P. Snutch, Paolo Tammaro, Jinbin Tian, James S. Trimmer, Charlotte Van den Eynde, Paola Vergani, Joris Vriens, Stephen G. Waxman, Aguan D. Wei, Brenda T. Winn, Heike Wulff, Haoxing Xu, Fan Yang, Lixia Yue, Xiaoli Zhang, Michael Zhu   +86 more
wiley   +1 more source

Integrating scFv into xMAP Assays for the Detection of Marine Toxins

Toxins, 2016
Marine toxins, such as saxitoxin and domoic acid are associated with algae blooms and can bioaccumulate in shell fish which present both health and economic concerns.
Lisa C. Shriver-Lake, Jinny L. Liu, P. Audrey Brozozog Lee, Ellen R. Goldman, Richard Dietrich, Erwin Märtlbauer, George P. Anderson   +6 more
doaj   +1 more source

Toxic Algae Contamination and Demand for Shellfish: A Case Study of Demand for Mussels in Montreal [PDF]

Toxic algae blooms are a worldwide phenomena, which appear to be increasing in frequency and severity. These natural events cause product contaminations that often have significant economic consequences, including supply interruptions due to closed ...
Brooks, Priscilla M., Miller, Christopher J., Roheim, Cathy A.   +2 more
core   +1 more source