Results 61 to 70 of about 13,668,831 (239)

Attitudes towards organ donation in Malta in the last decade [PDF]

, 2006
Organ transplantation is possibly one of the few cases when even though the medical professionals have the expertise to carry out transplants of certain organs, and even though a person may have financial resources to cover every possible cost, the ...
Lauri, Mary Anne
core  

Kidney transplantation from uncontrolled donation after circulatory death donors maintained by nECMO has long-term outcomes comparable to standard criteria donation after brain death

, 2018
Uncontrolled donation after circulatory death (uDCD) increases organ availability for kidney transplant (KT) with short-term outcomes similar to those obtained from donation after brain death (DBD) donors.
Justo Alonso, Iago, Molina Martín, María, Rodríguez Antolín, Alfredo, Hernández Martínez, Eduardo Rafael, Guerrero Ramos, Félix, González Monte, Esther, Andrés Belmonte, Amado, Morales Ruiz, Enrique, Pamplona Casamayor, Manuel, Cavero, Teresa, Fernández Ruiz, Mario, Villar, Alicia, Cabrera, Jimena, Praga Terente, Manuel, Chico, Mario, Polanco, Natalia, Hernández Vicente, Ana, Gutiérrez Martínez, Eduardo, Rosa, Federico de la   +18 more
core   +1 more source

The gift of life: Understanding the experiences of organ donor families

Journal of Family Medicine and Primary Care
Introduction: The family being a fundamental unit of society in India, the decisions regarding organ donation are usually made collectively within the family, involving not only the immediate family but also extended family members.
Parul Gupta, Vijay Kumar Tadia, Vipin Koushal   +2 more
doaj   +1 more source

Development of key interventions and quality indicators for the management of an adult potential donor after brain death: a RAND modified Delphi approach

BMC Health Services Research, 2018
Background A substantial degree of variability in practices exists amongst donor hospitals regarding the donor detection, determination of brain death, application of donor management techniques or achievement of donor management goals.
Pieter Hoste, Eric Hoste, Patrick Ferdinande, Koenraad Vandewoude, Dirk Vogelaers, Ann Van Hecke, Xavier Rogiers, Kristof Eeckloo, Kris Vanhaecht, on behalf of the Donation after Brain Death Study Group   +9 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

How I Manage the Adult Potential Organ Donor: Donation After Cardiac Death (Part 2)

, 2010
To address the gap between organs available for transplant and the number of patients on the transplant waiting list, the Joint Commission on the Accreditation of Healthcare Organizations, Institute of Medicine, United Network for Organ Sharing and the ...
Jennifer A. Frontera, Frontera, Jennifer A.   +1 more
core   +1 more source

Organ and tissue donation: exploring the needs of families

, 2003
Relatives of potential organ donors are the most critical link in maintaining organ availability, as they must express their lack of objection before organ retrieval may take place. The often sudden and unexpected nature of the death of a potential organ
Long-Sutehall, Tracy, Sque, Magi, Payne, Sheila   +2 more
core   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source