Results 91 to 100 of about 12,814,856 (242)

What do bereaved parents want from professionals after the sudden death of their child : a systematic review of the literature [PDF]

, 2014
Background The death of a child is a devastating event for parents. In many high income countries, following an unexpected death, there are formal investigations to find the cause of death as part of wider integrated child death review processes.
Sidebotham, Peter, Garstang, J; id_orcid, Frances Griffiths, Joanna Garstang, Griffiths, F, Sidebotham, P, Peter Sidebotham, Garstang, Joanna, Griffiths, Frances   +8 more
core   +2 more sources

Near‐Infrared Light‐Activated Polydopamine Nanoparticles Conjugated With Transferrin Peptides for Enhanced Brain Accumulation

Advanced Healthcare Materials, EarlyView.
This study demonstrates that Tf‐PDA NPs combine a receptor‐mediated targeting with mild photothermal activation to enhance nanoparticle accumulation in the brain. NIR‐activated Tf‐PDA NPs increase BBB permeability to NPs in vitro and in vivo without inducing cytotoxicity or adverse immune responses.
Rafaela Ferrão, Susana Simões, Paulo Rodrigues‐Santos, Vitor Francisco, Akhilesh Rai, Lino Ferreira   +5 more
wiley   +1 more source

Prediction of kidney transplant outcome based on different DGF definitions in Chinese deceased donation

BMC Nephrology, 2019
Background Delayed graft function (DGF) is an important complication of kidney transplantation and can be diagnosed according to different definitions. DGF has been suggested to be associated with the long-term outcome of kidney transplantation surgery ...
Xiao-jun Hu, Jin Zheng, Yang Li, Xiao-hui Tian, Pu-xun Tian, He-li Xiang, Xiao-ming Pan, Chen-guang Ding, Xiao-ming Ding, Wu-jun Xue   +9 more
doaj   +1 more source

Static Cold Storage with Mitochondria-Targeted Hydrogen Sulfide Donor Improves Renal Graft Function in an Ex Vivo Porcine Model of Controlled Donation-after-Cardiac-Death Kidney Transplantation. [PDF]

Int J Mol Sci, 2023
Dugbartey GJ, Juriasingani S, Richard-Mohamed M, Rasmussen A, Levine M, Liu W, Haig A, Whiteman M, Arp J, Luke PPW, Sener A.   +10 more
europepmc   +1 more source

Self‐Assembling Copolymers Encapsulating Single Endothelial Cells Induce Endogenous ECM Deposition and Vascular Regeneration

Advanced Materials, EarlyView.
This study presents the first demonstration of stable sub‐50‐micron single‐cell GPM vesicles fabricated through the intrinsic self‐assembly of an amphiphilic copolymer. Hierarchical assembly of cell containing GPM vesicles into microspheres enable tunable, sustained cell delivery with immune protection.
Viola B. Morris, Sangho Lee, Kalp Soni, Simon He, Matthew Huang, Dandan Chen, Dae Hoon Lee, Kyung Hee Kim, Seonggeon Cho, Laura Pencea, Divit Jain, Young‐Sup Yoon   +11 more
wiley   +1 more source

Mitofilin Preservation Mitigates Cardiac Injury in Donation-After-Circulatory-Death Hearts

Cells
Donation after circulatory death (DCD) involves unavoidable ischemia–reperfusion injury (IRI). Mitochondrial permeability transition pore (MPTP) opening plays a critical role in DCD heart injury. Activation of ubiquitous calpains, including calpain-1 and
Qun Chen, Zachary Kiernan, Gina Labate, Oluwatoyin Akande, Edward J. Lesnefsky, Mohammed Quader   +5 more
doaj   +1 more source

Survival benefit of accepting kidneys from older donation after cardiac death donors. [PDF]

Am J Transplant, 2021
Yu S, Long JJ, Yu Y, Bowring MG, Motter JD, Ishaque T, Desai N, Segev DL, Garonzik-Wang JM, Massie AB.   +9 more
europepmc   +1 more source

Microgels Enable iPSCs to Assemble, Expand, and Differentiate Into Organoids—From Sizable to High‐Throughput

Advanced Materials, EarlyView.
A chemically defined PEG‐based microgel platform enables scalable, reproducible production of three‐dimensional microgel‐iPSC constructs in multiple sizes. The system is compatible with high‐throughput automation and supports human iPSC expansion and differentiation within a single construct, including directed differentiation into cardiac organoids ...
Laura Klasen, Matthias Mork, Ramin Nasehi, Vasudha Turuvekere Krishnamurthy, Kira Zeevaert, Aaron Babendreyer, Jacopo Di Russo, Wolfgang Wagner, Laura De Laporte   +8 more
wiley   +1 more source

Hypothermic Oxygenated Perfusion Improves Vascular and Contractile Function by Preserving Endothelial Nitric Oxide Production in Cardiac Grafts Obtained With Donation After Circulatory Death

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Cardiac donation after circulatory death is a promising option to increase graft availability. Graft preservation with 30 minutes of hypothermic oxygenated perfusion (HOPE) before normothermic machine perfusion may improve cardiac recovery as ...
Manuel Egle, Natalia Mendez‐Carmona, Adrian Segiser, Selianne Graf, Matthias Siepe, Sarah Longnus   +5 more
doaj   +1 more source

Prolonged warm ischemia time leads to severe renal dysfunction of donation-after-cardiac death kidney grafts. [PDF]

Sci Rep, 2021
Urbanellis P, Mazilescu L, Kollmann D, Linares-Cervantes I, Kaths JM, Ganesh S, Oquendo F, Sharma M, Goto T, Noguchi Y, John R, Konvalinka A, Mucsi I, Ghanekar A, Bagli D, Robinson LA, Selzner M.   +16 more
europepmc   +1 more source