Results 121 to 130 of about 150,076 (297)

Friend, Not Foe: Lowered Tissue Reactivity to Long‐Term Polyimide Implants

Advanced Science, EarlyView.
The choice of optimal neural probe designs remains a major challenge in the field of neurotechnology. This study investigated the biocompatibility of several probe variations, including material, thickness, width, and implantation strategy. It highlights the clear advantage of soft polyimide probes over stiff silicon probes for better device ...
Corinne Orlemann, Laura M. De Santis, Paul Neering, Christian Boehler, Kirti Sharma, Arno Aarts, Tobias Holzhammer, Rik J. J. van Daal, Patrick Ruther, Maria Asplund, Roxana N. Kooijmans, Pieter R. Roelfsema   +11 more
wiley   +1 more source

Young Boy Rides Donkey

, 1951
A young boy is seated on a donkey during rodeo week.

core  

Determinant genetic markers of semen quality in livestock

Frontiers in Endocrinology
The reproductive efficiency of livestock is crucial for agricultural productivity and economic sustainability. One critical factor in successful fertilization and the viability of offspring is the quality of semen.
Muhammad Zahoor Khan, Wenting Chen, Saima Naz, Xiaotong Liu, Huili Liang, Yinghui Chen, Xiyan Kou, Yihong Liu, Iqra Ashraf, Ying Han, Yongdong Peng, Changfa Wang, Muhammad Zahoor   +12 more
doaj   +1 more source

Remote Magnetomechanical Neuromodulation Uncovers Therapeutic Mechanisms for Alleviating Parkinsonian Symptoms in Freely Moving Mice

Advanced Science, EarlyView.
Magnetomechanical neuromodulation using magnetic nanodiscs enables remote activation of neurons. In a hemiparkinsonian mouse model, alternating magnetic fields actuate the nanodiscs to generate torque that opens mechanosensitive ion channels within the subthalamic nucleus, thereby modulating basal ganglia motor circuitry.
Anouk Wolters, Lorenzo Signorelli, Christian Herff, Sophia Gimple, Renzo Riemens, Gunter Kenis, Kim Rijkers, Hamed Shabani, Jyh‐Jang Sun, Yasin Temel, Hans Clusmann, Danijela Gregurec, Sarah‐Anna Hescham   +12 more
wiley   +1 more source

donkey-engine

donkey_Cent_ donkey-engine (steam pump) _NID_ donkey = donkey boiler (auxilim) donkey boy donkey engine ~ men donkey breakfast ~ boiler _OED_ donkey bay ~ engine

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donkey furnace

, 1973
donkey...the donkey furnace would be goin' all the winter, nearly all the winter.... (type of furnace used abaord ship which filled pipes with steam and helped to keep ship warm?)YesJ.D.A WIDDOWSON JUL 1973Used I and

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Advances in the Regulation of Lipid Metabolism by Non-Coding RNAs

Animals
Lipid metabolism is a fundamental biological process that ensures energy homeostasis and cellular integrity. This is an essential and complex biochemical process that is involved in energy storage and the maintaining of normal biological functions ...
Yongdong Peng, Anqi Liu, Qifei Zhu, Xiaotong Liu, Bingbing Cai, Zhiyu Yan, Jiwei Gao, Ruchang Zhu, Changfa Wang   +8 more
doaj   +1 more source

Kinsenoside Targets IDH1 to Restore Microglial Immune‐Metabolic Homeostasis for Alzheimer's Disease Therapy

Advanced Science, EarlyView.
Dysregulated TCA cycle contributes to Alzheimer's disease (AD) pathogenesis. Here, we show that microglial isocitrate dehydrogenase 1 (IDH1) is a critical driver. Elevated IDH1 disrupts citrate metabolism and mitochondrial function, exacerbating AD pathology.
Qianqian Li, Yajin Liao, Yan‐bo Zhao, Hongxing Wu, Tong Jin, Shuoshuo Li, Yuhan Liu, Peng Li, Songying Ouyang, Zekai Li, YuTing Xia, Qian Hua, Rui‐Yuan Pan, Zengqiang Yuan   +13 more
wiley   +1 more source

Gut microbiome regulation in equine animals: current understanding and future perspectives

Frontiers in Microbiology
The equine intestinal microbiome represents a complex and dynamic ecosystem that fundamentally influences host health and physiological function.
Fenglin Li, Xiangyu Kong, Muhammad Zahoor Khan, Lin Wei, Jinjin Wei, Mingxia Zhu, Guiqin Liu, Bingjian Huang, Changfa Wang, Zhenwei Zhang   +9 more
doaj   +1 more source

Secreted Nonstructural Protein 3 is a Pathogenic Determinant of Orbivirus

Advanced Science, EarlyView.
This study uncovers a conserved PIP2‐dependent secretory pathway of orbivirus NS3 that induces vascular leakage. Pharmacological disruption of PIP2‐NS3 interaction significantly reduces viral pathogenicity and provides protective efficacy in murine models, establishing PIP2‐mediated NS3 secretion as both a key virulence determinant and a promising ...
Junyong Guan, Dong Zhou, Ran Shao, Xing Liu, Jin Peng, Yingran Huang, Shuhui Qi, Cankun Xi, Menghang Wang, Bin Sun, Yinglin Qi, Xin Yin   +11 more
wiley   +1 more source