Results 41 to 50 of about 247,608 (349)

STAT3 expression is reduced in cardiac pericytes in HFpEF and its loss reduces cellular adhesion and induces pericyte senescence

open access: yesFEBS Letters, EarlyView.
Heart failure with preserved ejection fraction (HFpEF) accounts for half of the heart failure cases. It is characterised by microvascular dysfunction, associated with reduced pericyte coverage and diminished STAT3 expression in pericytes. Loss of STAT3 impairs pericyte adhesion, promotes senescence, and activates a pro‐fibrotic gene program.
Leah Rebecca Vanicek   +15 more
wiley   +1 more source

The ‘wonderful’ donkey – Of real and fabled donkeys

open access: yesHTS Teologiese Studies / Theological Studies, 2019
An ethological appreciation of the donkey has confirmed that it is a special and unique animal. The donkey is a well-adapted, sensitive, sociable, intelligent and notably loyal animal. Their so-called ‘stubbornness’ (dumbness) points rather to a species-specific intelligence to survive.
openaire   +4 more sources

The Old Testament prophecy about the ass's foal of the Messiah and donkey-terminology [PDF]

open access: yes, 2012
The donkey is charged with a rich, important biblical symbolism. Usually the kings choose a strong and combatant animal for ceremonies – a thoroughbred horse, an imposing elephant or even a camel.
Almalech, Mony
core  

Protonophore activity of short‐chain fatty acids induces their intracellular accumulation and acidification

open access: yesFEBS Letters, EarlyView.
The protonated form of butyrate, as well as other short‐chain fatty acids (SCFAs), is membrane permeable. In acidic extracellular environments, this can lead to intracellular accumulation of SCFAs and cytosolic acidification. This phenomenon will be particularly relevant in acidic environments such as the large intestine or tumor microenvironments ...
Muwei Jiang   +2 more
wiley   +1 more source

Optimization of Enzymatic Hydrolysis Conditions and Micromorphology of Bone Collagen Peptides from Donkey with Iron Chelating Ability

open access: yesLiang you shipin ke-ji, 2022
In order to make full use of donkey bone resources, a method was developed to hydrolyze donkey bone with protease to obtain donkey bone collagen peptide.
MAO Jia-min   +7 more
doaj   +1 more source

A Relapsed Donkey [PDF]

open access: yesNature, 1876
SOME years ago on one of the Lucknow roads I met a “Dhobi” (washerman) with some donkeys. I send you a picture of one of them, made by a native artist. It shows, I think, the relationship between the zebra and the donkey better than many which I have seen.
openaire   +2 more sources

The effectiveness of faecal removal methods of pasture management to control the cyathostomin burden of donkeys [PDF]

open access: yes, 2014
Background: The level of anthelmintic resistance within some cyathostomin parasite populations has increased to the level where sole reliance on anthelmintic-based control protocols is not possible.
Burden, Faith A   +5 more
core   +2 more sources

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

open access: yesMolecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu   +11 more
wiley   +1 more source

Comment on Ssuna et al. Animal Welfare Guidelines for International Development Organisations in the Global South. Animals 2024, 14, 2012

open access: yesAnimals
International Development Organisations (IDOs) undertake critical work to improve the lives of people across the world, particularly in the Global South [...]
Jo Hockenhull   +4 more
doaj   +1 more source

Tense and the Logic of Change [PDF]

open access: yes, 1992
In this paper it is shown how the DRT (Discourse Representation Theory) treatment of temporal anaphora can be formalized within a version of Montague Semantics that is based on classical type ...
Muskens, Reinhard
core   +5 more sources

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