Results 31 to 40 of about 144,899 (217)

An investigation of genetic diversity in three Dezhou donkey original breeding farms

open access: yesScientific Reports, 2023
Dezhou donkey is one of the excellent large donkey breeds in China. In our study, eight microsatellite markers were used to genotype from each of three populations of Chinese Dezhou donkeys: 67 individuals in Liaocheng (pop1), 103 individuals in Binzhou ...
Tianqi Wang   +9 more
doaj   +1 more source

Identification of equine herpesvirus 8 in donkey abortion: a case report

open access: yesVirology Journal, 2022
Background Equine herpesvirus-8 (EHV-8) is one of the most economically significant viruses that infect mammals of the genus Equus worldwide, which cause severe respiratory diseases and abortion in horses.
Tongtong Wang   +9 more
doaj   +1 more source

A novel SNP in NKX1-2 gene is associated with carcass traits in Dezhou donkey

open access: yesBMC Genomic Data, 2023
Background At present, donkey meat in the market shows an imbalance between supply and demand, and there is an urgent need to cultivate a meat-type Dezhou donkey breed.
Xinrui Wang   +11 more
doaj   +1 more source

The welfare and access to veterinary health services of mules working the mountain trails in the Gorkha region, Nepal

open access: yesAustral Journal of Veterinary Sciences, 2023
Working equid populations are mainly present in low to middle-income countries, their work directly contributing to the lives of people reliant on their presence.
Tamlin Watson   +5 more
doaj   +1 more source

Effect of Sperm Cryopreservation in Farm Animals Using Nanotechnology

open access: yesAnimals, 2022
Sperm cryopreservation is one of the sublime biotechnologies for assisted reproduction. In recent decades, there has been an increasing trend in the use of preserved semen.
Muhammad Faheem Akhtar   +6 more
doaj   +1 more source

A unified STR profiling system across multiple species with whole genome sequencing data

open access: yesBMC Bioinformatics, 2019
Background Short tandem repeats (STRs) serve as genetic markers in forensic scenes due to their high polymorphism in eukaryotic genomes. A variety of STRs profiling systems have been developed for species including human, dog, cat, cattle, etc ...
Yilin Liu   +4 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Polymorphism detection of PRKG2 gene and its association with the number of thoracolumbar vertebrae and carcass traits in Dezhou donkey

open access: yesBMC Genomic Data, 2023
Background Previous studies have shown that the protein kinase cGMP-dependent 2 (PRKG2) gene is associated with dwarfism in humans, dogo Argentines, and Angus cattle, as well as with height and osteoblastogenesis in humans.
Tianqi Wang   +12 more
doaj   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

The Fibrolytic Enzyme Profiles and the Composition of Fungal Communities in Donkey Cecum-Colon Ecosystem

open access: yesAnimals, 2022
The fibrolytic enzymes and the hindgut fungi in donkey cecum-colon ecosystem play an important role in dietary fiber digestion. A better understanding of the fibrolytic enzyme profiles and the fungal community along donkey caecum and colon is key for ...
Zhenwei Zhang   +4 more
doaj   +1 more source

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