Results 41 to 50 of about 259,781 (292)
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Effect of Sperm Cryopreservation in Farm Animals Using Nanotechnology
Sperm cryopreservation is one of the sublime biotechnologies for assisted reproduction. In recent decades, there has been an increasing trend in the use of preserved semen.
Muhammad Faheem Akhtar +6 more
doaj +1 more source
The Old Testament prophecy about the ass's foal of the Messiah and donkey-terminology [PDF]
The donkey is charged with a rich, important biblical symbolism. Usually the kings choose a strong and combatant animal for ceremonies – a thoroughbred horse, an imposing elephant or even a camel.
Almalech, Mony
core
Serial fiction, the End? [PDF]
Andrew McGonigal presents some interesting data concerning truth in serial fictions.1 Such data has been taken by McGonigal, Cameron and Caplan to motivate some form of contextualism or relativism.
Walters, Lee
core +1 more source
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
MP4 video‘Donkey and Tiger’ was told by Rgyal mtshan in A mdo Tibetan. Rta rgyugs, a subdivision of Rka phug Administrative Village, is a farming village located in Khams ra Town, Gcan tsa County Town, Rma lho Tibetan Autonomous Prefecture, Qinghai ...
Rdo rje don 'grub
core
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
International Development Organisations (IDOs) undertake critical work to improve the lives of people across the world, particularly in the Global South [...]
Jo Hockenhull +4 more
doaj +1 more source
May the force be with you: an investigation into logging methods using donkeys
Working equids represent major sources of energy worldwide, and assume an increasingly important role in line with increasing requirements for sustainable energy.
João Rodrigues +7 more
doaj +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source

