Results 71 to 80 of about 137,112 (292)

A hospital for donkeys

, 2020
coverage ...
openaire   +2 more sources

Exploring the Role of Stent Strut Geometry in Cellular Behavior: An In Vitro Chip Model to Understand In‐Stent Restenosis

Advanced Materials Interfaces, EarlyView.
An engineered in vitro platform mimicking stent strut cross‐sectional shapes reveals how geometry influences cell behavior. Sharp‐cornered geometries promote cell proliferation and matrix alignment, while rounded shapes reduce these effects. The findings align with clinical outcomes and suggest intracellular tension as a key driver, offering a ...
Emmie J.D. Schoutens, Juul Verbakel, Heleen M.M. van Beusekom, Jaap M.J. den Toonder, Olaf van der Sluis, Jan de Boer   +5 more
wiley   +1 more source

Remote‐Controlled Wireless Bioelectronics for Fluoxetine Therapy to Promote Wound Healing in a Porcine Model

Advanced Materials Technologies, EarlyView.
A wireless bioelectronic ion pump platform is developed for controlled fluoxetine delivery for wound healing in a large mammal model. Over 3 days, treated wounds showed 37% greater re‐epithelialization and a 33% lower ratio of pro‐inflammatory to reparative macrophages.
Houpu Li, Narges Asefifeyzabadi, Kaelan Schorger, Prabhat Baniya, Hsin‐ya Yang, Maryam Tebyani, Alexie Barbee, Wan Shen Hee, Anthony Gallegos, Kan Zhu, Cynthia Recendez, Fan Lu, George Luka, Sujung Kim, Koushik Devarajan, Tiffany Nguyen, Sydnie Figuerres, Celeste Franco, Elham Aslankoohi, Héctor Carrión, Narges Norouzi, Marcella Gomez, Min Zhao, Roslyn Rivkah Isseroff, Mircea Teodorescu, Marco Rolandi   +25 more
wiley   +1 more source

Microfluidic Platform with Local Oxygen Sensors Demonstrates That 3D Blood Vessel Networks Exhibit Time‐Dependent Changes in Oxygen Concentrations During Their Formation and Perfusion

Advanced Materials Technologies, EarlyView.
Novel OoC platform with functional vascular networks highlights challenges in oxygenation. This study uses optical oxygen sensors to monitor oxygen during vascular formation, revealing perfusion limitations and highlighting the need for better oxygenation strategies.
Tarek Gensheimer, Stefanie Fuchs, Laura E. de Heus, Kim Vermeul, Torsten Mayr, Andries v.d. Meer   +5 more
wiley   +1 more source

Lycium barbarum Glycopeptide Alleviates Neomycin‐Induced Ototoxicity by Inhibiting Tryptophan Hydroxylase‐Mediated Serotonin Biosynthesis

Advanced Science, EarlyView.
Lycium barbarum glycopeptide (LBGP), which is further extracted from Lycium barbarum polysaccharides, exhibits significant protective effects against neomycin‐induced hearing dysfunction including oxidative stress in cochlea and loss of key cells in cochlea.
Yunhao Wu, Li Zhang, Shengda Cao, Jingwen Zhang, Cheng Li, Yunlong Shan, Qiuping Liu, Zhexiong Yu, Qiaojun Fang, Yuhua Zhang, Xiaolong Fu, Kwok‐Fai So, Renjie Chai   +12 more
wiley   +1 more source

Data-Independent Acquisition Method for In-Depth Proteomic Screening of Donkey Meat

Agriculture
Donkey meat has gained popularity as an emerging meat product due to its superior nutritional value and distinctive flavor. Despite this, research on the molecular mechanisms that contribute to meat quality, particularly within the field of proteomics ...
Liyuan Wang, Honglei Qu, Xinrui Wang, Tianqi Wang, Qiugang Ma, Muhammad Zahoor Khan, Mingxia Zhu, Changfa Wang, Wenqiang Liu, Wenqiong Chai   +9 more
doaj   +1 more source

RONIN/HCF1‐TFEB Axis Protects Against D‐Galactose‐Induced Cochlear Hair Cell Senescence Through Autophagy Activation

Advanced Science, EarlyView.
D‐galactose (D‐gal) induced inner ear hair cell senescence by inhibiting TFEB transcription. RONIN/HCF1 promotes TFEB transcription to prevent cochlear HCs from D‐gal‐induced senescence through autophagy activation. Abstract Age‐related hearing loss is characterized by senescent inner ear hair cells (HCs) and reduced autophagy.
Yongjie Wei, Yuhua Zhang, Wei Cao, Nan Cheng, Yun Xiao, Yongjun Zhu, Yan Xu, Lei Zhang, Lingna Guo, Jun Song, Su‐hua Sha, Buwei Shao, Fang Ma, Jingwen Yang, Zheng Ying, Zuhong He, Renjie Chai, Qiaojun Fang, Jianming Yang   +18 more
wiley   +1 more source

Bipolar-Staining Bacilli of the Fowl-Cholera Type as the Cause of Wide-Spread, Acute, and Fatal Pneumonia in Horse and Donkey Young Stock in India [PDF]

, 1909
E. Clive Webb
openalex   +1 more source

A Multifunctional Nanodelivery System Modified by Fusion Peptides Acts as Teriparatide Carrier for Noise‐Induced Hearing Loss Therapy

Advanced Science, EarlyView.
The fusion peptide LR27‐modified thermosensitive nanodelivery system exhibits both hair cell targeting and inner ear penetrating properties. This system sustainably and effectively delivers PTH1‐34 to the inner ear of a hearing loss mouse model via the synergistic effects of multiple peptides, achieving satisfactory hearing protection through ...
Jiawen Li, Zhuowen Hao, Fangzi Ke, Zhihui Liu, Weilong Wang, Sihui Wen, Fan Wu, Bowen Xu, Miao He, Shengyu Zou, Xiong Chen, Jingfeng Li, Zuhong He   +12 more
wiley   +1 more source

The Nuclear Localization of ACLY Guards Early Embryo Development Through Recruiting P300 and HAT1 to Promote Histone Acetylation and Transcription

Advanced Science, EarlyView.
ACLY is vital for early embryo development. IGF‐1 activates AKT to phosphorylate ACLY, driving its nuclear localization and recruitment of HATs (P300/HAT1), boosting acetyl‐CoA production and histone acetylation for transcriptional activation. Conversely, ACLY deficiency (via knockdown, knockout, or AKT inhibition) reduces nuclear acetyl‐CoA, disrupts ...
Yerong Ma, Yingyi Zhang, Weijie Yang, Xiaomei Tong, Siya Liu, Yan Zhou, Mengjia Qiu, Huifang Jiang, Zhanhong Hu, Peipei Ren, Yan Rong, Mengru Lai, Jiamin Jin, Fei Huang, Liujian Ouyang, Feng Zhou, Heng‐Yu Fan, Yin‐Li Zhang, Songying Zhang   +18 more
wiley   +1 more source