Results 51 to 60 of about 44,178 (276)

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

open access: yesFEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru   +6 more
wiley   +1 more source

Morphometric Study of Erythrocytes in Donkeys and Horses

open access: yesContemporary Agriculture
The aim of this study was to examine morphometric values of erythrocytes in donkeys and horses. While the hematological and biochemical profiles of horses and donkeys have been previously documented in literature, there are no precise morphometric data ...
Erdeljan Mihajlo   +8 more
doaj   +1 more source

Sacrifice and business : a comparative study of ritual and commercial cattle slaughtering in Tenkodogo, Burkina Faso [PDF]

open access: yes, 2006
All over the world meat plays an important role in the nutrition of people. Mostly it is considered to be a special source of strength and health. In many peoples' minds the consumption of animal products, such as muscle, fat, blood, inner organs and ...
Zimmermann, Hans
core  

A Vascular Microphysiological Model of Lung Fibrosis Reveals That Myofibroblasts and IPF Patient‐Derived Fibroblasts Impair Angiogenesis and Vasculogenesis

open access: yesAdvanced Functional Materials, EarlyView.
A microphysiological lung fibrosis model recapitulates myofibroblast–vascular interactions. Induced myofibroblasts and patient‐derived IPF fibroblasts impair angiogenesis and increase vascular permeability via TGF‐β1–driven signaling. Pharmacological interventions with SB 431542 and VEGF supplementation restore vascular morphology and barrier function.
Elena Cambria   +7 more
wiley   +1 more source

What's metaphysical about metaphysical necessity? [PDF]

open access: yes, 2009
I begin by contrasting three approaches one can take to the distinction between the essential and accidental properties: an ontological, a deflationary, and a mind-dependent approach.
Hawley   +5 more
core   +1 more source

Bimetallic Nanoreactor Activates cGAS‐STING Pathway via mtDNA Release for Cancer Metalloimmunotherapy

open access: yesAdvanced Functional Materials, EarlyView.
A bimetallic Mn–Ca nanoreactor (MCC) is developed as a non‐nucleotide STING nanoagonist for cancer metalloimmunotherapy. MCC induces Ca2+ overload and hydroxyl radical generation, resulting in mitochondrial damage and mtDNA release. The released mtDNA cooperates with Mn2+ to robustly activate cGAS–STING signaling.
Xin Wang Mo   +7 more
wiley   +1 more source

Voices from the Source: Struggles with Local Water Security in Ethiopia [PDF]

open access: yes, 2013
This report explores local water security in two different sites in Ethiopia, Shinile and Konso. This issue cannot be reduced to a single diagnostic such as measures of water use or presence of an improved source.
Alan Nicol   +5 more
core  

On the Probability of Plenitude [PDF]

open access: yes, 2020
I examine what the mathematical theory of random structures can teach us about the probability of Plenitude, a thesis closely related to David Lewis's modal realism.
Russell, Jeffrey Sanford
core  

Oral Dosed Organo‐Silica Nanoparticles Restore Glucose Homeostasis and β‐Cell Function in Diabetes Rats

open access: yesAdvanced Functional Materials, EarlyView.
An oral nanoplatform, MOP@T@D, which can maintain glucose homeostasis and restore islet β cells in diabetic rats is developed. It achieves efficient intestinal absorption and liver‐targeted delivery. The nanoparticle disintegrates only in response to hyperglycemia to release insulin on demand and provides antioxidant protection through selenoprotein ...
Chenxiao Chu   +14 more
wiley   +1 more source

Necropsy survey of gastric ulcers in a population of aged donkeys: prevalence, lesion description and risk factors

open access: yesAnimal, 2009
There is no information about the prevalence of gastric ulceration in donkeys or potential risk factors for its presence in donkeys. The donkey is a stoic, hardy animal that has not previously been thought to suffer from this disease.
F.A. Burden   +3 more
doaj   +1 more source

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